Tuberostemonine (Standard)
Tuberostemonine (Standard) is the analytical standard of Tuberostemonine. This product is intended for research and analytical applications. Tuberostemonine is a stenine alkaloid that can be isolated from Stemona tuberosa and Stemona sessifolia. Tuberostemonine is an antimalarial agent that has inhibitory activity Ferredoxin-NADP+ reductases (FNRs) from Plasmodium falciparum (PfFNR). Tuberostemonine has a level of activity as a feeding deterrent .
For research use only. We do not sell to patients.
- CAS No.: 6879-01-2
- Formula: C22H33NO4
- Molecular Weight:375.50
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 6879-01-2
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Molecular Weight 375.50
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Formula C22H33NO4
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SMILES
[H][C@@]([C@]1([H])[C@@]23[H])(CCCCN1[C@]([H])([C@@]4([H])OC([C@@H](C)C4)=O)C3)[C@@H](CC)[C@]([C@]2([H])[C@@H]5C)([H])OC5=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Pudjiastuti P, et al. Inhibitory Activity and Docking Analysis of Antimalarial Agents from Stemona sp. toward Ferredoxin-NADP+ Reductase from Malaria Parasites. J Parasitol Res. 2018 Aug 26;2018:3469132. [Content Brief]
[2]. Wipf, P., & Spencer, S. R. (2005). Asymmetric total syntheses of tuberostemonine, didehydrotuberostemonine, and 13-epituberostemonine. Journal of the American Chemical Society, 127(1), 225–235. [Content Brief]
[3]. Zhou, X., et al., (2009). Oral absorption and antitussive activity of tuberostemonine alkaloids from the roots of Stemona tuberosa. Planta medica, 75(6), 575–580. [Content Brief]
[4]. Jung, K. H., et al., (2016). The therapeutic effects of tuberostemonine against cigarette smoke-induced acute lung inflammation in mice. European journal of pharmacology, 774, 80–86. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)