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Results for "

73

" in MedChemExpress (MCE) Product Catalog:

By Targets:	CD73 (32) 17β-HSD (1) 5-HT Receptor (11) AAK1 (1) Acyltransferase (2) Adenylate Cyclase (1) Adrenergic Receptor (6) Amylases (1) Amyloid-β (1) Antibiotic (1) Apoptosis (14) ASCT (1) ATM/ATR (1) Autophagy (10) Bacterial (6) Bcl-2 Family (1) BCRP (1) Beta-secretase (1) Bradykinin Receptor (1) c-Kit (4) c-Met/HGFR (1) Casein Kinase (1) CaSR (2) CCR (1) CD38 (1) CDK (5) Cholinesterase (ChE) (1) COX (3) CXCR (1) Cytochrome P450 (1) Deubiquitinase (1) DNA Methyltransferase (2) DNA/RNA Synthesis (5) Dopamine Receptor (6) Dopamine β-hydroxylase (1) Drug Metabolite (1) EAAT (1) EGFR (6) Endogenous Metabolite (2) Endothelin Receptor (2) Epigenetic Reader Domain (3) ERK (1) Estrogen Receptor/ERR (2) FAK (1) Farnesyl Transferase (1) FGFR (5) FLT3 (5) Fluorescent Dye (4) Fungal (3) GABA Receptor (2) GCGR (1) GHSR (2) GLP Receptor (1) Glucosidase (2) GLUT (1) GSK-3 (1) HBV (1) HDAC (3) Histamine Receptor (2) Histone Acetyltransferase (1) Histone Methyltransferase (4) HIV (2) ICMT (1) IGF-1R (1) iGluR (2) Indoleamine 2,3-Dioxygenase (IDO) (1) Influenza Virus (1) Insulin Receptor (1) Interleukin Related (1) IRAK (1) Isotope-Labeled Compounds (4) JAK (4) Ligands for Target Protein for PROTAC (1) Lipoxygenase (2) LPL Receptor (1) mAChR (5) MAP4K (1) MDM-2/p53 (3) Microtubule/Tubulin (3) MMP (1) nAChR (1) NF-κB (3) Nuclear Factor of activated T Cells (NFAT) (1) Nucleoside Antimetabolite/Analog (1) Opioid Receptor (1) Oxytocin Receptor (1) P-glycoprotein (1) P2X Receptor (1) Parasite (5) PD-1/PD-L1 (1) PDGFR (6) Phosphatase (8) Phosphodiesterase (PDE) (4) PI3K (2) Pim (1) PKC (1) Platelet-activating Factor Receptor (PAFR) (1) Potassium Channel (9) PPAR (4) Prostaglandin Receptor (1) PROTACs (1) Proton Pump (1) Raf (6) Ras (2) Reactive Oxygen Species (2) RET (6) ROCK (2) SARS-CoV (2) Ser/Thr Protease (1) SGLT (1) SHP2 (3) Sigma Receptor (1) Sirtuin (1) Small Interfering RNA (siRNA) (3) Sodium Channel (2) STAT (1) TAM Receptor (3) Tau Protein (2) TET Protein (2) TGF-β Receptor (1) Tie (3) TNF Receptor (1) Toll-like Receptor (TLR) (1) Topoisomerase (3) VEGFR (6)
By Research Areas:	Cancer (127) Cardiovascular Disease (17) Endocrinology (4) Infection (21) Inflammation/Immunology (41) Metabolic Disease (29) Neurological Disease (42)
Click Chemistry:	Alkynes (1)

247

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Targets Recommended: CD73

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-131967

CD73-IN-4	CD73	Inflammation/Immunology Cancer
CD73-IN-4 is a potent and selective methylenephosphonic acid *CD73* inhibitor, with an IC₅₀ of 2.6 nM for human CD73. CD73-IN-4 is potential for the research of cancer immunology .

HY-N7181

7,3'-Dihydroxy-5'-methoxyisoflavone Pterosonin E	Others	Cancer
7,3'-Dihydroxy-5'-methoxyisoflavone (Pterosonin E) is an arylcoumarin. 7,3'-Dihydroxy-5'-methoxyisoflavone can be used for various biochemical studies .

HY-N7806

7,3'-Di-O-Methylorobol

Others Others

7,3'-Di-O-Methylorobol is a flavone that can be isolated from Sophora japonica .

7,3'-Di-O-Methylorobol	Others	Others
7,3'-Di-O-Methylorobol is a flavone that can be isolated from Sophora japonica .

HY-152582

7-(3-Deoxy-β-D-erythro-pentofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine	Nucleoside Antimetabolite/Analog	Others
7-(3-Deoxy-β-D-erythro-pentofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-155279

Antifungal agent 73	Fungal	Infection
Antifungal agent 73 (compound A32) is an antifungal agent for azole-resistant candidiasis. Antifungal agent 73 disrupts the fungal cell wall and cell membrane. Antifungal agent 73 shows potent in vivo antifungal activity against pathogenic fungi and fluconazole-resistant strains .

HY-143232

Antibacterial agent 73	Fungal Bacterial	Infection Cancer
Antibacterial agent 73 (compound 7a) is a potent antimicrobial agent. Antibacterial agent 73 exhibits very good antitubercular activity (MIC=0.65 µg/mL) against Mtb H37Rv. Antibacterial agent 73 shows good activity against fungal and bacterial. Antibacterial agent 73 also shows cytotoxicity in MCF-7 breast cancer cell lines, with IC₅₀ of 8.20 μM .

HY-122214

AC-73 3 Publications Verification	Autophagy	Cancer
AC-73 is a first specific, orally active inhibitor of cluster of differentiation 147 (CD147), which specifically disrupts CD147 dimerization, thereby mainly suppressing the CD147/ERK1/2/STAT3/MMP-2 pathways. AC-73 inhibits the motility and invasion of hepatocellular carcinoma cells . AC-73 is also an anti-proliferative agent and an inducer of autophagy in leukemic cells .

HY-144209

CD73-IN-6

CD73 Cancer

CD73-IN-6 is a CD73 inhibitor extracted from patent WO2022007677A1 compound 2. CD73-IN-6 can be used for the research of cancer .

CD73-IN-6	CD73	Cancer
CD73-IN-6 is a *CD73* inhibitor extracted from patent WO2022007677A1 compound 2. CD73-IN-6 can be used for the research of cancer .

HY-147918

Anticancer agent 73	DNA/RNA Synthesis	Cancer
Anticancer agent 73 (compound CIB-3b) is a anticancer agent, potently targeting TAR RNA-binding protein 2 (TRBP) and disrupts its interaction with Dicer. Anticancer agent 73 can rebalance the expression profile of oncogenic or tumor-suppressive miRNAs. Anticancer agent 73 suppresses the proliferation and metastasis of HCC in vitro and in vivo .

HY-108034

GET73	Others	Neurological Disease
GET73 is a γ-hydroxybutyric acid (GHB) analog, a naturally occurring neurotransmitter. GET73 has anti-alcohol and anxiolytic properties. GET73 significantly affects glutamate transmission in the hippocampus .

HY-147594

CD73-IN-13	CD73	Cancer
CD73-IN-13 is a potent inhibitor of *CD73. CD73 is closely associated with tumor growth, angiogenesis and metastasis. CD73*-IN-13 be used for preparing a medicament for tumor-related diseases (extracted from patent CN114437039A, compound 7) .

HY-147593

CD73-IN-12	CD73	Cancer
CD73-IN-12 is a potent inhibitor of *CD73. CD73 is closely associated with tumor growth, angiogenesis and metastasis. CD73-IN-12 be used for preparing a medicament for tumor-related diseases (extracted from patent CN114437038A, compound 9) . CD73*-IN-12 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-145334

CD73-IN-5

CD73 Cancer

CD73-IN-5 is a potent and selective non-nucleotide small molecule inhibitor of CD73 (IC₅₀ = 19 nM).

CD73-IN-5	CD73	Cancer
CD73-IN-5 is a potent and selective non-nucleotide small molecule inhibitor of *CD73* (IC₅₀ = 19 nM).

HY-152074

CD73-IN-14	CD73	Cancer
D73-IN-14 is a potent, selective and orally active *CD73* inhibitor with an IC₅₀ value of 0.17 nM. CD73-IN-14 increases the number of tumor-infiltrating CD8 ⁺ cells and shows anti-tumor activity . CD73-IN-14 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-137246

CD73-IN-3	CD73	Cancer
CD73-IN-3 is a potent *CD73* inhibitor (IC₅₀=7.3 nM in Calu6 human cell assay). CD73-IN-3, example 2 extracted from patent WO2019168744 A1, has the potential for cancer research .

HY-104028B

(S)-BAY 73-6691	Others	Neurological Disease
(S)-BAY 73-6691 is the isomer of BAY 73-6691 (HY-104028), and can be used as an experimental control. BAY 73-6691 ((R)-BAY 73-6691) is a potent, brain penetrant, and selective PDE9A inhibitor .

HY-147588

CD73-IN-7	CD73	Cancer
CD73-IN-7 is a potent inhibitor of *CD73. CD73 can catalyze the production of adenosine from extracellular 5'-phosphate adenosine (5'-AMP), and adenosine can induce immunosuppressive effects and promote tumor proliferation and/or metastasis. CD73*-IN-7 be used for preparing a medicament for tumor-related diseases (extracted from patent WO2022052886A1, compound 13) .

HY-147589

CD73-IN-8	CD73	Cancer
CD73-IN-8 is a potent inhibitor of *CD73. CD73 can catalyze the production of adenosine from extracellular 5'-phosphate adenosine (5'-AMP), and adenosine can induce immunosuppressive effects and promote tumor proliferation and/or metastasis. CD73*-IN-8 be used for preparing a medicament for tumor-related diseases (extracted from patent WO2022052886A1, compound 57) .

HY-147590

CD73-IN-9	CD73	Inflammation/Immunology
CD73-IN-9 is a potent inhibitor of *CD73. CD73 can catalyze the production of adenosine from extracellular 5'-phosphate adenosine (5'-AMP), and adenosine can induce immunosuppressive effects and promote tumor proliferation and/or metastasis. CD73*-IN-9 be used for preparing a medicament for tumor-related diseases (extracted from patent WO2022068929A1, compound 2) .

HY-147592

CD73-IN-11	CD73	Inflammation/Immunology Cancer
CD73-IN-11 is a potent inhibitor of *CD73. CD73 can catalyze the production of adenosine from extracellular 5'-phosphate adenosine (5'-AMP), and adenosine can induce immunosuppressive effects and promote tumor proliferation and/or metastasis. CD73*-IN-11 be used for preparing a medicament for tumor-related diseases (extracted from patent WO2022068929A1, compound 24) .

HY-147591

CD73-IN-10	CD73	Inflammation/Immunology Cancer
CD73-IN-10 is a potent inhibitor of *CD73. CD73 can catalyze the production of adenosine from extracellular 5'-phosphate adenosine (5'-AMP), and adenosine can induce immunosuppressive effects and promote tumor proliferation and/or metastasis. CD73*-IN-10 be used for preparing a medicament for tumor-related diseases (extracted from patent WO2022068929A1, compound 4) .

HY-131435

CD73-IN-2

CD73 Cancer

CD73-IN-2 is a potent CD73 inhibitor extracted from WO2020151707A1, example 1, has an IC₅₀ of 0.09 nM .
HY-104028

BAY 73-6691

1 Publications Verification

Phosphodiesterase (PDE) Neurological Disease

BAY 73-6691 ((R)-BAY 73-6691) is a potent, brain penetrant, and selective PDE9A inhibitor .
HY-D0499

Pigment yellow 73

Fluorescent Dye

Pigment yellow 73 is a disazomethine dye with solid-state fluorescence.a biologically active chemical.
HY-103695

CD73-IN-1

CD73 Cancer

CD73-IN-1 is an inhibitor of CD73 which can be used in the treatment of cancer extracted from patent WO 2017153952 A1, example 80.
HY-D0515

Disperse red 73

Fluorescent Dye

Disperse red 73 is a red dye derived from anthraquinone. It is used in plastics, textiles and cosmetics.

CD73-IN-2	CD73	Cancer
CD73-IN-2 is a potent *CD73* inhibitor extracted from WO2020151707A1, example 1, has an IC₅₀ of 0.09 nM .

BAY 73-6691 1 Publications Verification	Phosphodiesterase (PDE)	Neurological Disease
BAY 73-6691 ((R)-BAY 73-6691) is a potent, brain penetrant, and selective PDE9A inhibitor .

Pigment yellow 73	Fluorescent Dye
Pigment yellow 73 is a disazomethine dye with solid-state fluorescence.a biologically active chemical.

CD73-IN-1	CD73	Cancer
CD73-IN-1 is an inhibitor of *CD73* which can be used in the treatment of cancer extracted from patent WO 2017153952 A1, example 80.

Disperse red 73	Fluorescent Dye
Disperse red 73 is a red dye derived from anthraquinone. It is used in plastics, textiles and cosmetics.

HY-151286

Antitumor agent-73	STAT	Cancer
Antitumor agent-73 is a Diosgenin (HY-N0177) derivative, which inhibits STAT3 signaling and activates Pdia3/ERp57 exogenously. Antitumor agent-73 shows potent anti-tumor activity against various cancer cell lines, 7.9-341.7-fold stronger than Diosgenin .

HY-151882

EGFR-IN-73

EGFR Cancer

EGFR-IN-73 (Compound 3f) is a potent inhibitor for the most common EGFR mutation EGFR Del19 with an IC₅₀ of 119 nM .

EGFR-IN-73	EGFR	Cancer
EGFR-IN-73 (Compound 3f) is a potent inhibitor for the most common EGFR mutation EGFR Del19 with an IC₅₀ of 119 nM .

HY-133118

6RK73 1 Publications Verification	Deubiquitinase	Cancer
6RK73 is a covalent irreversible and specific UCHL1 inhibitor with an IC₅₀ of 0.23 µM. 6RK73 shows almost no inhibition of UCHL3 (IC₅₀=236 µM). 6RK73 specifically inhibit UCHL1 activity in breast cancer .

HY-D0555

C.I. Disperse orange 73

Fluorescent Dye Others

C.I. Disperse orange 73 is an orange-orange dye commonly used for fiber dyeing.
HY-162111

SARS-CoV-2-IN-73

SARS-CoV Infection

SARS-CoV-2-IN-73 (compound 4) is a SARS-CoV-2 RNA-dependent RNA polymerase (RdRp) blocker .

C.I. Disperse orange 73	Fluorescent Dye	Others
C.I. Disperse orange 73 is an orange-orange dye commonly used for fiber dyeing.

SARS-CoV-2-IN-73	SARS-CoV	Infection
SARS-CoV-2-IN-73 (compound 4) is a SARS-CoV-2 RNA-dependent RNA polymerase (RdRp) blocker .

HY-118941

BAY 73-1449	Prostaglandin Receptor	Cardiovascular Disease
BAY 73-1449 is a selective antagonist of prostacyclin receptor (IP), with high potency (IC₅₀ of less than 0.1 nM) in cAMP assays in Human HEL cells and rat DRG. BAY 73-1449 can be used in the research of lowering blood pressure .

HY-157722

HSD17B13-IN-73	17β-HSD	Metabolic Disease
HSD17B13-IN-73 (Compound 85) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC₅₀ value of < 0.1 μM for estradiol. HSD17B13-IN-73 can be used for research on liver diseases or metabolic disorders .

HY-104028A

BAY 73-6691 racemate

Phosphodiesterase (PDE) Neurological Disease

BAY 73-6691 racemate is a phosphodiesterase 9 inhibitor extracted from patent WO 2017070293 A1.

BAY 73-6691 racemate	Phosphodiesterase (PDE)	Neurological Disease
BAY 73-6691 racemate is a phosphodiesterase 9 inhibitor extracted from patent WO 2017070293 A1.

HY-101864

Blarcamesine hydrochloride 2 Publications Verification Anavex 2-73	Sigma Receptor	Neurological Disease Cancer
Blarcamesine hydrochloride (Anavex 2-73) is a Sigma-1 Receptor agonist with an IC₅₀ of 860 nM.

HY-RS02310

CDC73 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
CDC73 Human Pre-designed siRNA Set A contains three designed siRNAs for CDC73 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

CDC73 Human Pre-designed siRNA Set A CDC73 Human Pre-designed siRNA Set A

HY-RS14924

TP73 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
TP73 Human Pre-designed siRNA Set A contains three designed siRNAs for TP73 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TP73 Human Pre-designed siRNA Set A TP73 Human Pre-designed siRNA Set A

HY-RS15794

WDR73 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
WDR73 Human Pre-designed siRNA Set A contains three designed siRNAs for WDR73 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

WDR73 Human Pre-designed siRNA Set A WDR73 Human Pre-designed siRNA Set A

HY-12445

Asnuciclib 2 Publications Verification CDKI-73; LS-007	CDK Apoptosis	Inflammation/Immunology Cancer
Asnuciclib (CDKI-73; LS-007) is an orally active and highly efficacious CDK9 inhibitor, with K_i values of 4 nM, 4 nM and 3 nM for CDK9, CDK1 and CDK2, respectively. Asnuciclib down-regulates the RNAPII phosphorylation. Asnuciclib is also a novel pharmacological inhibitor of Rab11 cargo delivery and innate immune secretion .

HY-14758

Adipiplon NG2-73	GABA Receptor	Neurological Disease
Adipiplon (NG2-73) is a selective GABA_A receptor positive allosteric modulator. Adipiplon is particularly useful in the research of a variety of central nervous system (CNS) disorders.

HY-13308

Regorafenib Hydrochloride 45+ Cited Publications BAY 73-4506 hydrochloride	VEGFR Autophagy PDGFR Raf RET	Cancer
Regorafenib Hydrochloride (BAY 73-4506 hydrochloride) is a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1 with IC₅₀s of 13/4.2/46, 22, 7, 1.5 and 2.5 nM, respectively .

HY-P3260

5′-Nucleotidase, Microorganism CD73; 5′-NT	Endogenous Metabolite	Metabolic Disease
5′-Nucleotidase, Microorganism (CD73) is an intrinsic membrane glycoprotein present as an ectoenzyme. 5′-Nucleotidase catalyzes hydrolysis of 5-nucleotides to their corresponding nucleosides .

HY-P99558

Timigutuzumab GEXMab73; GT-MAb7.3-GEX; TrastuzuMab-GEX	EGFR	Cancer
Timigutuzumab (GEXMab73) is a humanized monoclonal antibody that targets ErbB2. Timigutuzumab can be used for the research of cancer .

HY-P4972

Tau Peptide (45-73) (Exon 2/Insert 1 Domain)

Tau Protein Neurological Disease

Tau Peptide (45-73) (Exon 2/Insert 1 Domain) is aTau fragment.

Tau Peptide (45-73) (Exon 2/Insert 1 Domain)	Tau Protein	Neurological Disease
Tau Peptide (45-73) (Exon 2/Insert 1 Domain) is aTau fragment.

HY-10331

Regorafenib 45+ Cited Publications BAY 73-4506	VEGFR Autophagy PDGFR Raf RET c-Kit FGFR Tie	Cancer
Regorafenib (BAY 73-4506) is an orally active and potent multi-targeted receptor tyrosine kinase inhibitor, with IC₅₀ values of 13/4.2/46, 22, 7, 1.5 and 2.5 nM for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1, respectively. Regorafenib shows very robust antitumor and antiangiogenic activity .

HY-10331A

Regorafenib monohydrate 45+ Cited Publications BAY 73-4506 monohydrate	VEGFR Autophagy PDGFR Raf RET FGFR c-Kit Tie	Cancer
Regorafenib (BAY 73-4506) monohydrate is an orally active and potent multi-targeted receptor tyrosine kinase inhibitor, with IC₅₀ values of 13/4.2/46, 22, 7, 1.5 and 2.5 nM for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1, respectively. Regorafenib monohydrate shows very robust antitumor and antiangiogenic activity .

HY-10331B

Regorafenib mesylate BAY 73-4506 mesylate	VEGFR PDGFR RET Raf c-Kit FGFR Autophagy Tie	Cancer
Regorafenib (BAY 73-4506) mesylate is an orally active and potent multi-targeted receptor tyrosine kinase inhibitor, with IC₅₀ values of 13/4.2/46, 22, 7, 1.5 and 2.5 nM for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1, respectively. Regorafenib mesylate shows very robust antitumor and antiangiogenic activity .

HY-10331S1

Regorafenib-13C,d3 BAY 73-4506-¹³C,d₃	VEGFR Autophagy PDGFR Raf RET	Cancer
Regorafenib- ¹³C,d₃ is the ¹³C- and deuterium labeled Regorafenib. Regorafenib (BAY 73-4506) is a multi-targeted receptor tyrosine kinase inhibitor with IC50s of 13/4.2/46, 22, 7, 1.5 and 2.5 nM for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1, respectively.

HY-P99181

Mupadolimab CPI-006	CD73	Infection Inflammation/Immunology
Mupadolimab (CPI-006) is an IgG1κ humanized FcγR binding-deficient anti-CD73 monoclonal antibody (mAb) that activates CD73 ^POS B cells .

HY-146759

ZM514	CD73	Cancer
ZM514 is a potent *CD73* inhibitor with IC₅₀s of 1.39 μM and 14.65 μM for hCD73 and mCD73, respectively. ZM514 has low cytotoxicity. ZM514 can be used for researching anticancer .

Cat. No.	Product Name	Target	Research Area

HY-P3829

Beacon (47-73)	Peptides	Metabolic Disease
Beacon (47-73) is a C-terminal peptide fragment 47-73 of Beacon, and Beacon is a protein of 73 amino acid. Beacon (47-73) can be used for metabolic syndrome research .

HY-P5354

FRETS-VWF73	Peptides	Others
FRETS-VWF73 is a biological active peptide. (FRETS-VWF73 is a very powerful Fluorescence-Quenching Substrate for the VWF cleaving protease ADAMTS-13. It is commonly used as a useful tool for the rapid measurement of ADAMTS-13 activity in plasma and is a predictive marker for various thrombotic diseases like TPP. Our new substrate FRETS-VWF73 can be easily used with a 96-well format in commercial plate readers.)

HY-P3830

Beacon (30-73)

Peptides Metabolic Disease

Beacon (30-73) is an ubiquitin-like protein, consisting of 44 amino acids .

HY-P5457

BMP-2 Epitope (73-92)	Peptides	Others
BMP-2 Epitope (73-92) is a biological active peptide. (This is amino acids 73 to 92 fragment of bone morphogenetic protein (BMP) knuckle epitope. It is a member of transforming growth factor beta (TGF-b). This peptide fragment is able to raise alkaline phosphate activity in murine multipotent mesenchymal cells.)

HY-P4847

pTH (73-84) (human)	Peptides	Others
pTH (73-84) (human) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4972

Tau Peptide (45-73) (Exon 2/Insert 1 Domain)

Tau Protein Neurological Disease

Tau Peptide (45-73) (Exon 2/Insert 1 Domain) is aTau fragment.

HY-P0003

Nesiritide Brain Natriuretic Peptide-32 human; BNP-32	Peptides	Cancer
Nesiritide (Brain Natriuretic Peptide-32 human) is an agonist of natriuretic peptide receptors (NPRs), with K_d values of 7.3 and 13 pM for NPR-A and NPR-C, respectively.

HY-P5832

BMP2-derived peptide	Peptides	Others
BMP2-derived peptide is a functional motif from positions 73 to 92 of the amino acid sequence of BMP-2. BMP2-derived peptide promotes osteogenic differentiation of bone marrow stromal cells (BMSCs) and enhances bone regeneration .

HY-12378

BQ-123 2 Publications Verification	Endothelin Receptor	Cardiovascular Disease
BQ-123 is a potent and selective endothelin A (ETA) receptor antagonist with an IC₅₀ of 7.3 nM and a K_i of 25 nM. BQ-123 inhibits endothelin-1-mediated proliferation of human pulmonary artery smooth muscle cells and lowers blood pressure in different rat models of hypertension .

HY-P5563

PP113	Bacterial	Infection
PP113 is an antimicrobial peptide is active against Gram-negative and Gram-positive bacteria, E.coli (MIC: 73.3 uM), B. subtilis (MIC: 23.3 uM), S. aureus (MIC: 13 uM), S. lutea (MIC: 16.7 uM), and B. pumilu (MIC: 23.3 uM) .

HY-125777A

α-Conotoxin Vc1.1 TFA	nAChR	Neurological Disease
α-Conotoxin Vc1.1 TFA is a disulfide-bonded peptide isolated from Conus victoriae and is a selective nAChR antagonist. α-Conotoxin Vc1.1 TFA inhibits α3α5β2, α3β2 and α3β4 with IC₅₀s of 7.2 μM, 7.3 μM and 4.2 μM, respectively, and has less inhibitory effect on other nAChR subtypes. α-Conotoxin Vc1.1 TFA has the potential for neuropathic pain reserach .

Cat. No.	Product Name	Target	Research Area

HY-P99181

Mupadolimab CPI-006	CD73	Infection Inflammation/Immunology
Mupadolimab (CPI-006) is an IgG1κ humanized FcγR binding-deficient anti-CD73 monoclonal antibody (mAb) that activates CD73 ^POS B cells .

HY-P990263

Anti-Mouse CD73 Antibody (TY/23)

Inhibitory Antibodies Others

Anti-Mouse CD73 Antibody (TY/23) is a rat-derived IgG2a, κ type antibody inhibitor, targeting to mouse CD73.
HY-P990245

Anti-Mouse FAP Antibody (73.3)

Inhibitory Antibodies Others

Anti-Mouse FAP Antibody (73.3) is a mouse-derived IgG1, κ type antibody inhibitor, targeting to mouse FAP.

HY-P99558

Timigutuzumab GEXMab73; GT-MAb7.3-GEX; TrastuzuMab-GEX	EGFR	Cancer
Timigutuzumab (GEXMab73) is a humanized monoclonal antibody that targets ErbB2. Timigutuzumab can be used for the research of cancer .

HY-P990160

Anti-Rat TCR alpha/beta Antibody (R73)	Inhibitory Antibodies	Others
Anti-Rat TCR alpha/beta Antibody (R73) is a mouse-derived IgG1, κ type antibody inhibitor, targeting to rat TCR alpha/beta.

HY-P99039

Oleclumab MEDI9447	CD73	Cancer
Oleclumab (MEDI9447) is a human IgG1λ monoclonal antibody targeting *CD73* and inhibits the exonuclease activity of the extracellular enzyme CD73. Oleclumab can adjust the composition of bone marrow and lymphoid infiltrating leukocyte populations in the tumor microenvironment and has anti-tumor activity .

HY-P99865

Dresbuxelimab

AK-119
CD73 Others

Dresbuxelimab (AK-119) is an IgG-κ monoclonal antibody targeting CD73. The expression system is usually CHO (Chinese Hamster Ovary) cells .

HY-P99841

Dalutrafusp alfa AGEN-1423; GS-1423	CD73 TGF-β Receptor	Inflammation/Immunology
Dalutrafusp alfa (AGEN-1423; GS-1423) is a specific bifunctional antibody against *CD73* and TGF-β, which is involved in the immunosuppressive pathway .

HY-P99169

Uliledlimab TJ004309	CD73	Cancer
Uliledlimab is a potent against CD73 humanizedized monoclonal antibody. Uliledlimab inhibits the conversion of extracellular adenosine monophosphate (AMP) to adenosine. Uliledlimab can be used in research of cancer .

HY-P99436

Anatumomab mafenatox ABR-214936	Inhibitory Antibodies	Inflammation/Immunology Cancer
Anatumomab mafenatox (ABR-214936) is a 73 KDa recombinant protein to recognize the tumor-associated antigen 5T4, which is widely expressing in malignancy. Anatumomab mafenatox is between a modified form of SEA and a murine Fab. The main side effects of Anatumomab mafenatox are reported to include fever, low blood pressure, pain, nausea and drowsiness .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-100583

(-)-(S)-Equol	Structural Classification Flavonoids Neurological Disease Classification of Application Fields Flavanols Source classification Phenols Polyphenols Metabolic Disease Endogenous metabolite Disease Research Fields	Estrogen Receptor/ERR Endogenous Metabolite
(-)-(S)-Equol is a high affinity ligand for estrogen receptor β with a K_i of 0.73 nM.

HY-N7181

7,3'-Dihydroxy-5'-methoxyisoflavone Pterosonin E	Leguminosae Pterocarpus soyauxii Taub. Source classification Plants	Others
7,3'-Dihydroxy-5'-methoxyisoflavone (Pterosonin E) is an arylcoumarin. 7,3'-Dihydroxy-5'-methoxyisoflavone can be used for various biochemical studies .

HY-N7806

7,3'-Di-O-Methylorobol	Structural Classification Flavonoids Flavones Leguminosae Source classification Sophora japonica (L.) Schott Plants	Others
7,3'-Di-O-Methylorobol is a flavone that can be isolated from Sophora japonica .

HY-N8578

Luteolin 7,3′-di-O-glucuronide	Marchantiaceae Structural Classification Flavonoids Marchantia polymorpha L. Flavones Source classification Plants	Others
Luteolin 7,3′-di-O-glucuronide is a flavonoid compound of the luteolin family .

HY-N0986

1,4,5,6-Tetrahydroxy-7-(3-methylbut-2-enyl)xanthone	Structural Classification Xanthones Garcinia xanthochymus Hook. f. ex T. Anders. Source classification Guttiferae Phenols Plants	Others
1,4,5,6-Tetrahydroxy-7-(3-methylbut-2-enyl)xanthone is a nature product that could be isolated from the stem barks of Garcinia xanthochymus. 1,4,5,6-Tetrahydroxy-7-(3-methylbut-2-enyl)xanthone has antiproliferative active. 1,4,5,6-Tetrahydroxy-7-(3-methylbut-2-enyl)xanthone can be used in research of cancer .

HY-N7310

Gomisin E	Structural Classification Classification of Application Fields Source classification Lignans Other Diseases Phenylpropanoids Plants Schisandraceae Disease Research Fields Schisandra chinensis (Turcz.) Baill.	Nuclear Factor of activated T Cells (NFAT)
Gomisin E, a dibenzocyclooctadiene lignan isolated from the fruits of Schizandra chinensis, inhibits NFAT transcription with an IC₅₀ of 4.73 μM .

HY-N11932

Piperulin A	Structural Classification Source classification Lignans Piperaceae Phenylpropanoids Plants Piper hongkongense C. de Candolle	Platelet-activating Factor Receptor (PAFR)
Piperulin A is a potent inhibitor of PAFR. Piperulin A inhibits the specific binding of PAFR on isolated rabbit platelet plasma membranes with an IC₅₀ of 7.3 μM .

HY-155236

Ancistrotecine B	Structural Classification Alkaloids Piperidine Alkaloids Source classification Ancistrocladus tectorius (Lour.) Merr. Plants Ancistrocladaceae	Sodium Channel
Ancistrotecine B (Compound 2) is a Nav1.7 channel inhibitor (IC₅₀: 0.73 μM). Ancistrotecine B relieves inflammatory pain in mice .

HY-N0014

Icariin Maximum Cited Publications 7 Publications Verification Ieariline	Cardiovascular Disease Flavonols Structural Classification Classification of Application Fields Anti-aging Source classification Plants Monophenols Flavonoids Phenols Epimedium brevicornu Maxim. Berberidaceae Inflammation/Immunology Disease Research Fields Cancer	Phosphodiesterase (PDE) PPAR Autophagy
Icariin is a flavonol glycoside. Icariin inhibits PDE5 and PDE4 activities with IC₅₀s of 432 nM and 73.50 μM, respectively. Icariin also is a PPARα activator.

HY-N7939

Celangulin XIX	Structural Classification Terpenoids Sesquiterpenes Source classification Celastraceae Celastrus angulatus Maxim. Plants	Others
Celangulin XIX is a insecticidal that can be isolated from Celastrus angulatu. Celangulin XIX has strong insecticidal activity against Mythimna separate with an ED₅₀ of 73.3 μg/g .

HY-N7031

(±)-Vasicine (±)-Peganine	Alkaloids Classification of Application Fields Zygophyllaceae Source classification Peganum harmala Linn. Plants Disease Research Fields Inflammation/Immunology	Proton Pump
(±)-Vasicine is the racemate of Vasicine. Vasicine (Peganine) significantly inhibits H ⁺-K ⁺-ATPase activity in vitro with an IC₅₀ of 73.47 μg/mL. Anti-ulcer activity. Vasicine shows significant anti-secretory, antioxidant and cytoprotective effect .

HY-113631

Amorfrutin B	Structural Classification Monophenols Leguminosae Source classification Phenols Amorpha fruticosaL. Plants	PPAR
Amorfrutin B is a highly potent natural peroxisome proliferation-activated receptor γ (PPARγ) agonist with oral activity with K_i values of 19 nM and EC₅₀ values of 73 nM, respectively. Amorfrutin B has hypoglycemic and neuroprotective activities .

HY-N3632

Methoxycoronarin D Coronarin D Me ether	Hedychium coronarium Koen. Structural Classification Terpenoids Source classification Diterpenoids Plants Zingiberaceae	NF-κB COX
Methoxycoronarin D can be isolated from Hedychium coronarium J. Koenig and is a potent inhibitor of NF-魏B with an IC₅₀ value of 7.3 渭M. Methoxycoronarin D is also a selective inhibitor of COX-1 with an IC₅₀ value of 0.9 渭M .

HY-N0014R

Icariin (Standard) Ieariline (Standard)	Cardiovascular Disease Structural Classification Classification of Application Fields Anti-aging Source classification Plants Flavonoids Phenols Epimedium brevicornu Maxim. Berberidaceae Inflammation/Immunology Disease Research Fields Cancer	Phosphodiesterase (PDE) PPAR Autophagy
Icariin (Standard) is the analytical standard of Icariin. This product is intended for research and analytical applications. Icariin is a flavonol glycoside. Icariin inhibits PDE5 and PDE4 activities with IC₅₀s of 432 nM and 73.50 μM, respectively. Icariin also is a PPARα activator.

HY-N3078

p-Hydroxyphenethyl trans-ferulate	Classification of Application Fields Simple Phenylpropanols Source classification Phenols Polyphenols Phenylpropanoids Plants Umbelliferae Disease Research Fields Endocrinology Echinacea angustifolia DC.	Glucosidase
p-Hydroxyphenethyl trans-ferulate has anti-hyperglycemic（yeast α-glucosidase，IC₅₀ 19.24 ± 1.73 µmol L-1）, antioxidant, and anti-inflammatory activities . p-Hydroxyphenethyl trans-ferulate shows inhibiting cancer preve

HY-N5130

Effusol	Juncus effusus Linn. Juncaceae Source classification Phenols Polyphenols Plants	Others
Effusol, a phenolic constituent from Juncus effuses, exhibits potent scavenging activity for DPPH and ABTS radicals, with IC₅₀ values of 79 μM and 2.73 μM, respectively. Effusol rescues CA1 LTP attenuated by corticosterone, defending the hippocampal function against stress-induced cognitive decline .

HY-N9505

Schisanlactone E Kadsulactone acid	Triterpenes Structural Classification Kadsura heteroclita (Roxb.) Craib Terpenoids Source classification Plants Schisandraceae	Others
Schisanlactone E is a triterpenoids that can be isolated from Kadsura heteroclita. Schisanlactone E exhibits moderate cytotoxic activity against Bel-7402, BGC-823, MCF-7 and HL-60 cell line with IC₅₀s of 68.33, 100, >100, 73.37 μM,respectively .

HY-N12177

Cryptosporioptide A	Structural Classification Flavonoids Microorganisms Source classification Other Flavonoids	Phosphatase
Cryptosporioptide A (Compound 3) is a pigment protein tyrosine phosphatase inhibitor derived from the insect-parasitic fungus Cordyceps gracilioides. Cryptosporioptide A inhibits PTP1B, SHP2, CDC25B, LAR and SHP1 enzymes with IC₅₀ of 7.3, 5.7, 7.6, >50, 4.9 μg/mL, respectively .

HY-N7634

Tectol	Infection Structural Classification other families Classification of Application Fields Source classification Phenols Polyphenols Plants Disease Research Fields	Farnesyl Transferase Parasite
Tectol, isolated from Lippia sidoides, exhibits significant activity against human leukemia cell lines HL60 and CEM . Tectol is a farnesyltransferase (FTase) inhibitor with IC₅₀s of 2.09 and 1.73 μM for human and T. brucei FTase, respectively. Tectol inhibits drug-resistant strain of P. falciparum (FcB1) with an IC₅₀ of 3.44 μM .

HY-N11288

Methyl salvionolate A	Structural Classification Labiatae Source classification Phenols Polyphenols Salvia yunnanensis C. H. Wright Plants	HIV
Methyl salvionolate A is a potent inhibitor of HIV-1. Methyl salvionolate A inhibits P24 antigen in HIV-1 infected MT-4 cell with an EC₅₀ of 1.62 μg/ml. Methyl salvionolate A also inhibits HIV-1 reverse transcriptase, protease and integrase with IC₅₀s of 50.58, 10.73 and 7.58 μg/ml, respectively .

HY-N3497

Isochamaejasmin	Structural Classification Flavonoids Thymelaeaceae Stellera chamaejasme Linn. Plants Other Flavonoids	NF-κB DNA/RNA Synthesis Parasite Apoptosis
Isochamaejasmin is a biflavonoid with anti-cancer, antiplasmodial and insecticidal activities. Isochamaejasmin displays a potent NF-κB (NF-κB) activation activity. Isochamaejasmin could cause DNA damage and induce apoptosis via the mitochondrial pathway in AW1 cells . Isochamaejasmin also has a moderate antiplasmodial activity (IC₅₀ of 7.3 μM for *P. falciparum*) and relatively low cytotoxicity (CC₅₀ of 29.0 μM) .

HY-N11844

Quercetin 3-(6″-caffeoylsophoroside)	Structural Classification Natural Products Cardamine hirsuta L. Source classification Plants Brassicaceae	Amylases
Quercetin 3-(6″-caffeoylsophoroside) is an orally active α-amylase inhibitor, with an IC₅₀ of 73.66 μg/mL. Quercetin 3-(6″-caffeoylsophoroside) presents in thehydro-methanolic extract of Cardamine hirsuta Linn. Quercetin 3-(6″-caffeoylsophoroside) shows the antidiabetic activities by oxidative stress reduction and α-amylase inhibition. Quercetin 3-(6″-caffeoylsophoroside) can be used for diabetes mellitus research .

HY-N3807

Enniatin B1 1 Publications Verification	Cardiovascular Disease Infection Alkaloids Microorganisms Classification of Application Fields Source classification Disease Research Fields	Acyltransferase ERK NF-κB
Enniatin B1 is a Fusarium mycotoxin. Enniatin B1 inhibits acyl-CoA: cholesterol acyltransferase (ACAT) activity with an IC₅₀ of 73 μM in an enzyme assay using rat liver microsomes . Enniatin B1 crosss the blood-brain barrier . Enniatin B1 decreases the activation of ERK (p44/p42). Enniatin B1 inhibits moderately TNF-α-induced NF-κB activation .

HY-N10621

3,5-Dimethoxy-2,7-phenanthrenediol	Structural Classification Combretaceae Phenols Polyphenols Plants Quisqualis indica Linn.	Others
3,5-Dimethoxy-2,7-phenanthrenediol (compound 2) is a phenanthrene compound isolated from the roots of Combretum laxum. 3,5-Dimethoxy-2,7-phenanthrenediol is cytotoxic to human cancer cell lines 786-0, MCF-7 and NCI/ADR-RES, with IC₅₀s of 73.26 μM, 118.40 μM and 83.99 μM respectively. 3,5-Dimethoxy-2,7-phenanthrenediol also has free radical scavenging activity with an IC₅₀ of 20.4 μM .

Species:	Human (18) Mouse (2) Rat (1) Cynomolgus (2)
Tag:	His (19) SUMO (1) Avi (2) GST (1) Fc (4)
Source:	HEK293 (14) Sf9 insect cells (1) E. coli (8)

Cat. No.	Compare	Product Name	Species	Source

HY-P7448

	CD73/5'-Nucleotidase Protein, Mouse (HEK293, His) rMuCD73, His; 5'-Nucleotidase; NT5E; CD-73	Mouse	HEK293
	CD73/5'-Nucleotidase Protein Protein, Mouse (HEK293, His) is a recombinant mouse CD73 expressed by HEK293 cells with His tag. CD73 is a cell surface enzyme that catalyzes the dephosphorylation of extracellular AMP to adenosine.

HY-P7449

	CD73/5'-Nucleotidase Protein, Rat (HEK293, His) rRtCD73, His; 5'-Nucleotidase; NT5E; CD-73	Rat	HEK293
	CD73/5'-Nucleotidase Protein, Rat (HEK293, His) is a 70-90 kDa rat CD73 protein with His-flag expressed by HEK293. Rat CD73 is a cell membrane protein that catalyzes the conversion of purine and pyrimidine ribo- and deoxyribonucleoside monophosphates to the corresponding nucleosides.

HY-P72209

	GOLM1 Protein, Human (His) bA379P1.3; C9orf155; Chromosome 9 open reading frame 155; Golgi membrane protein 1; Golgi membrane protein GP73; Golgi phosphoprotein 2; Golgi protein 73 kD ; Golgi protein 73kD ; GOLM 1; GOLM1; GOLM1_HUMAN; GOLPH 2; GOLPH2; GP 73; GP73; PSEC0257	Human	E. coli
	GOLM1 Protein, amid partial comprehension, acts as a cellular response protein to viral infections, with an intricate role yet to be fully understood. Interactions with DYM suggest potential links to cellular dynamics or host-virus interactions. Further investigation is crucial to delineate GOLM1's specific contributions and implications in cellular defense mechanisms against viral infections. GOLM1 Protein, Human (His) is the recombinant human-derived GOLM1 protein, expressed by E. coli , with N-6*His labeled tag. The total length of GOLM1 Protein, Human (His) is 366 a.a., with molecular weight of ~45.6 kDa.

HY-P72209A

	GOLM1 Protein, Human (His, Solution) bA379P1.3; C9orf155; Chromosome 9 open reading frame 155; Golgi membrane protein 1; Golgi membrane protein GP73; Golgi phosphoprotein 2; Golgi protein 73 kD ; Golgi protein 73kD ; GOLM 1; GOLM1; GOLM1_HUMAN; GOLPH 2; GOLPH2; GP 73; GP73; PSEC0257	Human	E. coli
	GOLM1 Protein, amid partial comprehension, acts as a cellular response protein to viral infections, with an intricate role yet to be fully understood. Interactions with DYM suggest potential links to cellular dynamics or host-virus interactions. Further investigation is crucial to delineate GOLM1's specific contributions and implications in cellular defense mechanisms against viral infections. GOLM1 Protein, Human (His, Solution) is the recombinant human-derived GOLM1 protein, expressed by E. coli , with N-6*His labeled tag. The total length of GOLM1 Protein, Human (His, Solution) is 366 a.a., with molecular weight of ~60 kDa.

HY-P7836

	CD73/5'-Nucleotidase Protein, Cynomolgus (521a.a, HEK293, His) rCynEcto-5'-nucleotidase/CD73, His; 5'-Nucleotidase; 5'-NT; Ecto-5'-Nucleotidase; CD73; NT5E; NT5; NTE	Cynomolgus	HEK293
	CD73/5'-Nucleotidase Protein, Cynomolgus (HEK 293, His) is a CD73 protein with a His-flag. CD73/5'-Nucleotidase Protein a zinc-dependent, 70 kDa homodimeric enzyme that binds to the cell membrane through a glycosyl phophatidylinositol (GPI) anchor.

HY-P70010

	CD73/5'-Nucleotidase Protein, Human (521a.a, HEK293, His) rHu5'-nucleotidase/CD73, His; 5'-Nucleotidase; 5'-NT; Ecto-5'-Nucleotidase; CD73; NT5E; NT5; NTE	Human	HEK293
	CD73/5'-Nucleotidase Protein hydrolyzes nucleotide monophosphates, favoring AMP as the primary substrate and showing a preference for ribonucleotide monophosphates. It releases inorganic phosphate and the corresponding nucleoside. CD73 also acts on other substrates, including IMP, UMP, GMP, CMP, dAMP, dCMP, dTMP, NAD, and NMN. CD73/5'-Nucleotidase Protein, Human (521a.a, HEK293, His) is the recombinant human-derived CD73/5'-Nucleotidase protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CD73/5'-Nucleotidase Protein, Human (521a.a, HEK293, His) is 521 a.a., with molecular weight of ~62.0 kDa.

HY-P73734

	p63/TP73L Protein, Human (sf9, His-GST) Tumor protein 63; p63; CUSP; TP63; p73L	Human	Sf9 insect cells
	p63/TP73L Protein, a sequence-specific DNA binding transcriptional regulator, exhibits diverse activities through its isoforms. Isoform 2 activates RIPK4 transcription, and the protein's engagement with TP73/p73 initiates p53/TP53-dependent apoptosis in response to genotoxic stress. p63 contributes to Notch signaling, potentially inducing JAG1 and JAG2, and influences epithelial morphogenesis. The balance between DeltaN-type and TA-type isoforms governs epithelial stem cell compartments, impacting epithelial stratification. Additionally, p63 is essential for limb formation and regulates the p21 promoter transcription. p63/TP73L Protein, Human (sf9, His-GST) is the recombinant human-derived p63/TP73L protein, expressed by Sf9 insect cells*, with N-His, N-GST labeled tag. The total length of p63/TP73L Protein, Human (sf9, His-GST) is 680 a.a., with molecular weight of ~125 kDa.

HY-P77534

	CD73/5'-Nucleotidase Protein, Human (Biotinylated, HEK293, His-Avi) 5-NT; 5'-Nucleotidase; CD73; E5NT; NT5E; NTE	Human	HEK293
	CD73/5'-Nucleotidase Protein hydrolyzes nucleotide monophosphates, favoring AMP as the primary substrate and showing a preference for ribonucleotide monophosphates. It releases inorganic phosphate and the corresponding nucleoside. CD73 also acts on other substrates, including IMP, UMP, GMP, CMP, dAMP, dCMP, dTMP, NAD, and NMN. CD73/5'-Nucleotidase Protein, Human (Biotinylated, HEK293, His) is the recombinant human-derived CD73/5'-Nucleotidase protein, expressed by HEK293 , with C-His labeled tag. The total length of CD73/5'-Nucleotidase Protein, Human (Biotinylated, HEK293, His) is 521 a.a., with molecular weight of ~59.2 KDa.

HY-P74272

	CD73/5'-Nucleotidase Protein, Human (T376A, HEK293, Fc) 5-NT; 5'-Nucleotidase; CD73; E5NT; NT5E; NTE	Human	HEK293
	CD73/5'-Nucleotidase Protein hydrolyzes nucleotide monophosphates, favoring AMP as the primary substrate and showing a preference for ribonucleotide monophosphates. It releases inorganic phosphate and the corresponding nucleoside. CD73 also acts on other substrates, including IMP, UMP, GMP, CMP, dAMP, dCMP, dTMP, NAD, and NMN. CD73/5'-Nucleotidase Protein, Human (T376A, HEK293, Fc) is the recombinant human-derived CD73/5'-Nucleotidase protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CD73/5'-Nucleotidase Protein, Human (T376A, HEK293, Fc) is 547 a.a., with molecular weight of ~84.5 kDa.

HY-P70492

	CD73/5'-Nucleotidase Protein, Human (T376A, M379T, HEK293, His) 5'-Nucleotidase; 5'-NT; Ecto-5'-Nucleotidase; CD73; NT5E; NT5; NTE	Human	HEK293
	CD73/5'-Nucleotidase Protein hydrolyzes nucleotide monophosphates, favoring AMP as the primary substrate and showing a preference for ribonucleotide monophosphates. It releases inorganic phosphate and the corresponding nucleoside. CD73 also acts on other substrates, including IMP, UMP, GMP, CMP, dAMP, dCMP, dTMP, NAD, and NMN. CD73/5'-Nucleotidase Protein, Human (T376A, M379T, HEK293, His) is the recombinant human-derived CD73/5'-Nucleotidase protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CD73/5'-Nucleotidase Protein, Human (T376A, M379T, HEK293, His) is 521 a.a., with molecular weight of ~62.0 kDa.

HY-P702646

GPX4 Protein, Human (U73S, His)

PHGPx; Glutathione peroxidase 4; GPx-4; GSHPx-4
Human E. coli

HY-P76966

	USH1C Protein, Human (His) Harmonin; Antigen NY-CO-38/NY-CO-37; Protein PDZ-73; AIE75	Human	E. coli
	USH1C, an anchoring and scaffolding protein, is crucial for cochlear hair cell mechanotransduction. It forms a network with USH1G, CDH23, and MYO7A, contributing to the development and maintenance of hair cell bundles. As part of the intermicrovillar adhesion complex (IMAC), USH1C regulates brush border differentiation, influencing microvilli organization and length. It recruits CDHR2, CDHR5, and MYO7B to microvilli tips, participating in complexes like IMAC, USH1C/USH1G/MYO7A, and interacting with various proteins, highlighting its multifaceted role. USH1C Protein, Human (His) is the recombinant human-derived USH1C protein, expressed by E. coli, with N-6*His labeled tag. The total length of USH1C Protein, Human (His) is 552 a.a., with molecular weight of ~70 kDa.

HY-P78536

	VEGFR-2 Protein, Human (HEK293, mFc) CD309; KDR; VEGFR; VEGFR2; VEGFR-21; FLK1; KRD1; Ly73	Human	HEK293
	VEGFR-2 protein is a tyrosine protein kinase receptor for VEGFA, VEGFC and VEGFD and is critical in angiogenesis, blood vessel development and embryonic hematopoiesis. It promotes endothelial cell function and actin cytoskeletal reorganization. VEGFR-2 Protein, Human (HEK293, mFc) is the recombinant human-derived VEGFR-2 protein, expressed by HEK293 , with C-mFc labeled tag. The total length of VEGFR-2 Protein, Human (HEK293, mFc) is 745 a.a., with molecular weight of 150-200 kDa.

HY-P700850

	VEGFR-2 Protein, Human (Biotinylated, HEK293, mFc) CD309; KDR; VEGFR; VEGFR2; VEGFR-21; FLK1; KRD1; Ly73	Human	HEK293
	VEGFR-2 protein is a tyrosine protein kinase receptor for VEGFA, VEGFC and VEGFD and is critical in angiogenesis, blood vessel development and embryonic hematopoiesis. It promotes endothelial cell function and actin cytoskeletal reorganization. VEGFR-2 Protein, Human (Biotinylated, HEK293, mFc) is the recombinant human-derived VEGFR-2 protein, expressed by HEK293 , with C-mFc labeled tag. The total length of VEGFR-2 Protein, Human (Biotinylated, HEK293, mFc) is 745 a.a., with molecular weight of 135-160 kDa.

HY-P78231

	VEGFR-2 Protein, Human (Biotinylated, HEK293, His-Avi) CD309; KDR; VEGFR; VEGFR2; VEGFR-21; FLK1; KRD1; Ly73	Human	HEK293
	VEGFR-2 protein is a tyrosine protein kinase receptor for VEGFA, VEGFC and VEGFD and is critical in angiogenesis, blood vessel development and embryonic hematopoiesis. It promotes endothelial cell function and actin cytoskeletal reorganization. VEGFR-2 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived VEGFR-2 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of VEGFR-2 Protein, Human (Biotinylated, HEK293, His-Avi) is 745 a.a., with molecular weight of 115-140 kDa.

HY-P71654

	ERVW-1 Protein, Human (His-SUMO) ERVW-1; ERVWE1; Syncytin-1; Endogenous retrovirus group W member 1; Env-W; Envelope polyprotein gPr73; Enverin	Human	E. coli
	The ERVW-1 protein is an endogenous retroviral envelope protein that retains fusogenic properties critical for trophoblast fusion and syncytium formation during placental morphogenesis. Its fusion ability involves binding to SLC1A4 and SLC1A5. ERVW-1 Protein, Human (His-SUMO) is the recombinant human-derived ERVW-1 protein, expressed by E. coli , with N-His, N-SUMO labeled tag. The total length of ERVW-1 Protein, Human (His-SUMO) is 423 a.a., with molecular weight of ~63.0 kDa.

HY-P77350

	DEFB127 Protein, Human (HEK293, Fc) Beta-defensin 127; Beta-defensin 27; DEFB-27; C20orf73	Human	HEK293
	The DEFB127 protein exhibits significant antibacterial activity, emphasizing its role in the innate immune system's defense against microbial threats. The ability of this protein to defend against bacterial pathogens emphasizes its importance as an effector molecule in host defense mechanisms. DEFB127 Protein, Human (HEK293, Fc) is the recombinant human-derived DEFB127 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of DEFB127 Protein, Human (HEK293, Fc) is 63 a.a., with molecular weight of ~36 KDa.

HY-P70879

	GOLM1 Protein, Human (HEK293, His) Golgi Membrane Protein 1; Golgi Membrane Protein GP73; Golgi Phosphoprotein 2; GOLM1; C9orf155; GOLPH2	Human	HEK293
	GOLM1 Protein, amid partial comprehension, acts as a cellular response protein to viral infections, with an intricate role yet to be fully understood. Interactions with DYM suggest potential links to cellular dynamics or host-virus interactions. Further investigation is crucial to delineate GOLM1's specific contributions and implications in cellular defense mechanisms against viral infections. GOLM1 Protein, Human (HEK293, His) is the recombinant human-derived GOLM1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of GOLM1 Protein, Human (HEK293, His) is 366 a.a., with molecular weight of ~66.0 kDa.

HY-P700980

	CXCL10 Protein, Cynomolgus (His) C-X-C motif chemokine 10; IP-10; CXCL10(1-73); CXCL10; INP10; SCYB10; C7; crg-2; gIP-10; IFI10	Cynomolgus	E. coli
	CXCL10 protein acts as a chemotactic factor for monocytes and T-lymphocytes, playing a crucial role in their migration in response to inflammatory signals. Through binding to CXCR3, CXCL10 selectively attracts monocytes and T-lymphocytes, positioning it as a key player in immune responses, contributing to the recruitment and activation of these immune cells in various physiological and pathological contexts. CXCL10 Protein, Cynomolgus (His) is the recombinant cynomolgus-derived CXCL10 protein, expressed by E. coli , with N-His labeled tag. The total length of CXCL10 Protein, Cynomolgus (His) is 65 a.a., with molecular weight of 12-14 kDa.

HY-P700729

	GGT1 Protein, Human (HEK293, His) Gamma-glutamyltransferase 1; GGT 1; CD224; GGT; GGT-1; GGTD; D22S672; D22S73; D22S732	Human	HEK293
	GGT1 Protein cleaves the gamma-glutamyl bond of extracellular glutathione, glutathione conjugates, and other gamma-glutamyl compounds. Its metabolism releases free glutamate and cysteinyl-glycine, hydrolyzed to cysteine and glycine. In the presence of high dipeptide concentrations, it catalyzes transpeptidation, forming new gamma-glutamyl compounds. GGT1 contributes to cysteine and glutathione homeostasis and converts leukotriene LTC4 to LTD4. Note: GGT1 seems to be inactive. GGT1 Protein, Human (HEK293, His) is the recombinant human-derived GGT1 protein, expressed by HEK293, with N-His labeled tag. The total length of GGT1 Protein, Human (HEK293, His) is 543 a.a., with molecular weight of 55-65 kDa (heavy chain) & 25-30 kDa (light chain), respectively.

HY-P700558

	GRO-alpha/CXCL1 Protein, Human (His) Growth-Regulated Alpha Protein; C-X-C Motif Chemokine 1; GRO-Alpha(1-73); Melanoma Growth Stimulatory Activity; MGSA; Neutrophil-Activating Protein 3; NAP-3; CXCL1; GRO; GRO1; GROA; MGSA; SCYB1	Human	E. coli
	GRO-alpha/CXCL1 protein attracts neutrophils and potentially contributes to inflammation through autocrine effects on endothelial cells. Processed forms of GRO-alpha, including GRO-alpha(4-73), GRO-alpha(5-73), and GRO-alpha(6-73), exhibit 30-fold greater chemotactic activity than the full-length protein. GRO-alpha/CXCL1 Protein, Human (His) is the recombinant human-derived GRO-alpha/CXCL1 protein, expressed by E. coli , with N-6*His labeled tag. The total length of GRO-alpha/CXCL1 Protein, Human (His) is 73 a.a., with molecular weight of 11.9 kDa.

HY-P700559

	GRO-alpha/CXCL1 Protein, Mouse (His) Growth-Regulated Alpha Protein; C-X-C Motif Chemokine 1; GRO-Alpha(1-73); Melanoma Growth Stimulatory Activity; MGSA; Neutrophil-Activating Protein 3; NAP-3; CXCL1; GRO; GRO1; GROA; MGSA; SCYB1	Mouse	E. coli
	GRO-alpha (CXCL1) Protein, with chemotactic properties, attracts and activates neutrophils during inflammatory responses. This hematoregulatory chemokine also suppresses hematopoietic progenitor cell proliferation, emphasizing its intricate role in hematopoiesis regulation. The truncated form KC(5-72) notably exhibits significantly enhanced hematopoietic activity in vitro. GRO-alpha/CXCL1 Protein, Mouse (His) is the recombinant mouse-derived GRO-alpha/CXCL1 protein, expressed by E. coli , with N-6*His labeled tag. The total length of GRO-alpha/CXCL1 Protein, Mouse (His) is 68 a.a., with molecular weight of 11.5 kDa.

HY-P70508

	GRO-alpha/CXCL1 Protein, Human (HEK293, His) 1 Publications Verification Growth-Regulated Alpha Protein; C-X-C Motif Chemokine 1; GRO-Alpha(1-73); Melanoma Growth Stimulatory Activity; MGSA; Neutrophil-Activating Protein 3; NAP-3; CXCL1; GRO; GRO1; GROA; MGSA; SCYB1	Human	HEK293
	CXCL1 (Chemokine (C-X-C motif) ligand 1), also known as GRO alpha, NAP-3 or MGSA, belongs to the sub-family of CXC chemokine. CXCL1 is involved in the development of many inflammatory diseases, including the induction of angiogenesis and recruitment of neutrophils. CXCL1 is produced by many cell types, and activates CXCR2 and, at high levels, CXCR1. GRO-alpha/CXCL1 Protein, Human (HEK293, His) is produced in HEK293 cells with a C-Terminal His-tag. It consists of 73 amino acids (A35-N107).

Cat. No.	Product Name	Chemical Structure

HY-12432S1

Gilteritinib-d8

Gilteritinib-d₈ is deuterium labeled Gilteritinib. Gilteritinib (ASP2215) is a potent and ATP-competitive FLT3/AXL inhibitor with IC50s of 0.29 nM/0.73 nM, respectively.

HY-10331S1

Regorafenib-13C,d3
Regorafenib- ¹³C,d₃ is the ¹³C- and deuterium labeled Regorafenib. Regorafenib (BAY 73-4506) is a multi-targeted receptor tyrosine kinase inhibitor with IC50s of 13/4.2/46, 22, 7, 1.5 and 2.5 nM for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1, respectively.

HY-13272S2

Dacomitinib-d10 dihydrochloride
Dacomitinib-d₁₀ (dihydrochloride) is the deuterium labeled Dacomitinib dihydrochloride. Dacomitinib (PF-00299804) dihydrochloride is a specific and irreversible inhibitor of the ERBB family of kinases with IC50s of 6 nM, 45.7 nM and 73.7 nM for EGFR, ERBB2, and ERBB4, respectively[1].

HY-13272S3

Dacomitinib-d10
Dacomitinib-d₁₀ is deuterium labeled Dacomitinib. Dacomitinib (PF-00299804) is a specific and irreversible inhibitor of the ERBB family of kinases with IC50s of 6 nM, 45.7 nM and 73.7 nM for EGFR, ERBB2, and ERBB4, respectively[1].

HY-A0030S

Fesoterodine-d7 fumarate
Fesoterodine-d₇ (fumarate) is the deuterium labeled Fesoterodine fumarate[1]. Fesoterodine Fumarate is an orally active, nonsubtype selective, competitive muscarinic receptor (mAChR) antagonist with pKi values of 8.0, 7.7, 7.4, 7.3, 7.5 for M1, M2, M3, M4, M5 receptors, respectively. Fesoterodine Fumarate is used for the overactive bladder (OAB)[2][3].

HY-13768S1

Topotecan-d6
Topotecan-d₆ is the deuterium labeled Topotecan. Topotecan (SKF 104864A; NSC 609669) is a Topoisomerase I inhibitor. The IC50 values of Topotecan at 24 h are 2.73±0.25 μM of U251 cells, 2.95±0.23 μM of U87 cells, 5.46±0.41 μM of GSCs-U251 and 5.95 μM of GSCs-U87[1][2].

HY-B0121BS2

Sumatriptan-d5
Sumatriptan-d₅ is deuterated labeled Sumatriptan (HY-B0121B). Sumatriptan (GR 43175) is an orally active 5-HT1 receptor agonist with IC₅₀s of 7.3 nm, 9.3nm and 17.8 nm for 5-HT_1D, 5-HT_1B and 5-HT_1F receptors, respectively. Sumatriptan can be used for migraine headache research .

Cat. No.	Product Name	Application	Reactivity

HY-P80387

CD73 Antibody (YA528)	WB, IHC-P	Human
CD73 Antibody (YA528) is a non-conjugated and Rabbit origined monoclonal antibody about 63 kDa, targeting to CD73. It can be used for WB,IHC-P assays with tag free, in the background of Human.

HY-P80388

CD73 Antibody (YA797)	WB, IHC-P, IF, FC	Human
CD73 Antibody (YA797) is a non-conjugated and Mouse origined monoclonal antibody about 63 kDa, targeting to CD73. It can be used for WB,IHC-P,IF,FC assays with tag free, in the background of Human.

HY-P81495

p73 Antibody (YA1240)

TP73; P73; Tumor protein p73; p53-like transcription factor; p53-related protein
IHC-P Human
HY-P81455

HRPT2/Parafibromin Antibody (YA1200)

CDC73; C1orf28, HRPT2; Parafibromin; Cell division cycle protein 73 homolog; Hyperparathyroidism 2 protein
IHC-P Human
HY-P83002

GOLPH2 Antibody (YA2747)

GOLPH2; GP73; GOLM1; Golgi protein 73kD; C9orf155
WB, IHC-P, ICC/IF, FC Human, Mouse, Rat
HY-P83322

Rad18 Antibody (YA3067)

E3 ubiquitin-protein ligase RAD18; hHR18; hRAD18; RAD18; RAD18; S. cerevisiae; homolog; RING finger protein 73; RNF73
WB, FC Human, Mouse, Rat
HY-P81786

p63 Antibody (YA1531)

EEC3; KET; LMS; SHFM4; TA p63 alpha; TP63; p51; p73H; p73L; tumor protein p63
WB, IHC-P, ICC/IF, FC Human, Mouse, Rat
HY-P81552

VEGF Receptor2 Antibody (YA1297)

FLK-1, VEGFR-2, CD309, KRD1, Ly73
WB, IF-Cell, IHC-P, IP Human, Rat
HY-P81700

HIF2 alpha Antibody (YA1445)

bHLHe73; ECYT4; EPAS 1; EPAS1; HIF2A; HLF; MOP 2; PASD2
WB, ICC/IF, FC Human, Mouse, Rat

HY-P80802

Phospho-c-Jun (Ser73) Antibody Transcription factor AP-1; Activator protein 1; AP1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog; p39	WB, IHC-P	Human, Mouse, Rat
Phospho-c-Jun (Ser73) Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 36 kDa, targeting to Phospho-c-Jun (Ser73). It can be used for WB,IHC-P assays with tag free, in the background of Human, Mouse, Rat.

HY-P82926

Cytokeratin 2e Antibody (YA2671) KRT2; KRT76; KRT3; KRT5; KRT6A; KRT6B; KRT6C; KRT71; KRT72; KRT73; KRT74; KRT75; KRT79; KRT8; KRT84; Keratin; type II cytoskeletal 2 epidermal; Keratin; type II cytoskeletal 2 oral; Keratin; type II cytoskeletal 3; Keratin; type II cytoskeletal 5; Keratin; type II cytoskeletal 6A; Keratin; type II cytoskeletal 6B; Keratin; type II cytoskeletal 6C; Keratin; type II cytoskeletal 71; Keratin; type II cytoskeletal 72; Keratin; type II cytoskeletal 73; Keratin; type II cytoskeletal 74	WB, IHC-P	Human

HY-P82861

Phospho-Jun/JunD (Ser73/Ser100) Antibody (YA2606) JUN; Transcription factor AP-1; Activator protein 1; AP1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog; p39; JUND; Transcription factor jun-D	WB, IP	Human, Mouse, Rat

HY-P81153

HIF 2 alpha Antibody Basic helix loop helix PAS protein MOP2; Basic-helix-loop-helix-PAS protein MOP2; bHLHe73; Class E basic helix-loop-helix protein 73; ECYT4; Endothelial PAS domain containing protein 1; Endothelial pas domain protein 1; Endothelial PAS domain-containing protein 1; EPAS 1; EPAS-1; EPAS1; EPAS1_HUMAN; HIF 1 alpha like factor; HIF-1-alpha-like factor; HIF-2-alpha; HIF2-alpha; HIF2A; HLF; Hypoxia inducible factor 2 alpha; Hypoxia inducible factor 2 alpha subunit; Hypoxia-inducible factor 2-alpha; Member of PAS protein 2; Member of pas superfamily 2; MOP 2; MOP2; PAS domain-containing protein 2; PASD2.	WB; ELISA; IHC-P; IHC-F; Flow-Cyt; IF	Human, Mouse, Rat(predicted: Pig, Cow, Horse)
HIF 2 alpha Antibody is an unconjugated, approximately 96 kDa, rabbit-derived, anti-HIF 2 alpha polyclonal antibody. HIF 2 alpha Antibody can be used for: WB, ELISA, IHC-P, IHC-F, Flow-Cyt, IF expriments in human, mouse, rat, and predicted: pig, cow, horse background without labeling.

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