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AKR1C3-IN-6 

Cat. No.: HY-146573
Handling Instructions

AKR1C3-IN-6 (Compound 1) is a potent, selective AKR1C3 inhibitor with IC50 values of 0.31 μM and 73.23 μM against AKR1C3 and AKR1C2, respectively. AKR1C3-IN-6 shows antitumor activity.

For research use only. We do not sell to patients.

AKR1C3-IN-6 Chemical Structure

AKR1C3-IN-6 Chemical Structure

CAS No. : 2137881-54-8

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Description

AKR1C3-IN-6 (Compound 1) is a potent, selective AKR1C3 inhibitor with IC50 values of 0.31 μM and 73.23 μM against AKR1C3 and AKR1C2, respectively. AKR1C3-IN-6 shows antitumor activity[1].

IC50 & Target

IC50: 0.31 μM (AKR1C3), 73.23 μM (AKR1C2)[1]

In Vitro

AKR1C3-IN-6 (Compound 1) shows antiproliferative activity with an IC50 of 81.40 ± 2.29 μM against prostate cancer cell line 22rv1[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

392.33

Formula

C18H15F3N4O3

CAS No.
SMILES

COC1=CC=C(C=C1)CN2N=NC(O)=C2C(NC3=CC(C(F)(F)F)=CC=C3)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Cell Assay

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

References
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AKR1C3-IN-6
Cat. No.:
HY-146573
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