2137881-54-8
2137881-54-8
Chemical Structure
AKR1C3-IN-6
- CAS No.: 2137881-54-8
- Formula:C18H15F3N4O3
- Molecular Weight:392.33
IUPAC Name: N-([1,1'-biphenyl]-3-yl)-4-hydroxy-1-(4-methoxybenzyl)-1H-1,2,3-triazole-5-carboxamide
InChIKey: IMCLZLUHJZCWCW-UHFFFAOYSA-N
SMILES: COC1=CC=C(C=C1)CN2N=NC(O)=C2C(NC3=CC(C(F)(F)F)=CC=C3)=O
Biological Activity: AKR1C3-IN-6 (Compound 1) is a potent, selective AKR1C3 inhibitor with IC50 values of 0.31 μM and 73.23 μM against AKR1C3 and AKR1C2, respectively. AKR1C3-IN-6 shows antitumor activity[1].
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AKR1C3-IN-6 | AKR1C3-IN-6 (Compound 1) is a potent, selective AKR1C3 inhibitor with IC50 values of 0.31 μM and 73.23 μM against AKR1C3 and AKR1C2, respectively. AKR1C3-IN-6 shows antitumor activity. | |||||||||||||||||||||
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References
Keywords
