1. Metabolic Enzyme/Protease
    Stem Cell/Wnt
    MAPK/ERK Pathway
    NF-κB
  2. Acyltransferase
    ERK
    NF-κB
  3. Enniatin B1

Enniatin B1 

Cat. No.: HY-N3807
Handling Instructions

Enniatin B1 is a Fusarium mycotoxin. Enniatin B1 inhibits acyl-CoA: cholesterol acyltransferase (ACAT) activity with an IC50 of 73 μM in an enzyme assay using rat liver microsomes. Enniatin B1 crosss the blood-brain barrier. Enniatin B1 decreases the activation of ERK (p44/p42). Enniatin B1 inhibits moderately TNF-α-induced NF-κB activation.

For research use only. We do not sell to patients.

Enniatin B1 Chemical Structure

Enniatin B1 Chemical Structure

CAS No. : 19914-20-6

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Description

Enniatin B1 is a Fusarium mycotoxin. Enniatin B1 inhibits acyl-CoA: cholesterol acyltransferase (ACAT) activity with an IC50 of 73 μM in an enzyme assay using rat liver microsomes[1]. Enniatin B1 crosss the blood-brain barrier[2]. Enniatin B1 decreases the activation of ERK (p44/p42). Enniatin B1 inhibits moderately TNF-α-induced NF-κB activation[3].

IC50 & Target[1][2]

ACAT

 

ERK

 

NF-κB

 

In Vitro

CCF-STTG1 cells are sensitive to Enniatin B1 (IC50=4.4 μM)[2].

Molecular Weight

653.85

Formula

C₃₄H₅₉N₃O₉

CAS No.

19914-20-6

SMILES

CC[[email protected]@H]([[email protected]]1([H])N(C([[email protected]](OC([[email protected]](N(C([[email protected]@H](C(C)C)OC([[email protected]](C(C)C)N(C)C([[email protected]](C(C)C)([H])OC1=O)=O)=O)=O)C)([H])C(C)C)=O)C(C)C)=O)C)C

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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Enniatin B1
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