country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-N3807S

Copy Link Print Information

Enniatin B1-¹³C₃₄

Enniatin B1-¹³C₃₄ is the ¹³C-labeled Enniatin B1 (HY-N3807). Enniatin B1 is a Fusarium mycotoxin. Enniatin B1 inhibits acyl-CoA: cholesterol acyltransferase (ACAT) activity with an IC₅₀ of 73 μM in an enzyme assay using rat liver microsomes. Enniatin B1 crosss the blood-brain barrier. Enniatin B1 decreases the activation of ERK (p44/p42). Enniatin B1 inhibits moderately TNF-α-induced NF-κB activation.

For research use only. We do not sell to patients.

Formula: ¹³C₃₄H₅₉N₃O₉
Molecular Weight:687.60

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (256 KB)

Enniatin B1-¹³C₃₄ Chemical Structure

Size

Price

Stock

Quantity

Amount: USD 0.00

* Please select Quantity before adding items.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
- Application
Chemical Information
Purity & Documentation
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Enniatin B1-¹³C₃₄ is the ¹³C-labeled Enniatin B1 (HY-N3807). Enniatin B1 is a Fusarium mycotoxin. Enniatin B1 inhibits acyl-CoA: cholesterol acyltransferase (ACAT) activity with an IC₅₀ of 73 μM in an enzyme assay using rat liver microsomes^[1]. Enniatin B1 crosss the blood-brain barrier^[2]. Enniatin B1 decreases the activation of ERK (p44/p42). Enniatin B1 inhibits moderately TNF-α-induced NF-κB activation^[3].

All NF-κB Isoforms :

All ERK Isoforms :

All Acyltransferase Isoforms :

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

Unlabeled Cas 19914-20-6
Molecular Weight 687.60
Formula ¹³C₃₄H₅₉N₃O₉
SMILES

[13CH3][13CH2][13C@@H]([13C@]1([H])N([13C]([13C@H](O[13C]([13C@](N([13C]([13C@@H]([13CH]([13CH3])[13CH3])O[13C]([13C@H]([13CH]([13CH3])[13CH3])N([13CH3])[13C]([13C@]([13CH]([13CH3])[13CH3])([H])O[13C]1=O)=O)=O)=O)[13CH3])([H])[13CH]([13CH3])[13CH3])=O)[13CH]([13CH3])[13CH3])=O)[13CH3])[13CH3]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.