1. Metabolic Enzyme/Protease
    Anti-infection
  2. Farnesyl Transferase
    Parasite
  3. Tectol

Tectol 

Cat. No.: HY-N7634
Handling Instructions

Tectol, isolated from Lippia sidoides, exhibits significant activity against human leukemia cell lines HL60 and CEM. Tectol is a farnesyltransferase (FTase) inhibitor with IC50s of 2.09 and 1.73 μM for human and T. brucei FTase, respectively. Tectol inhibits drug-resistant strain of P. falciparum (FcB1) with an IC50 of 3.44 μM.

For research use only. We do not sell to patients.

Tectol Chemical Structure

Tectol Chemical Structure

CAS No. : 24449-39-6

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Description

Tectol, isolated from Lippia sidoides, exhibits significant activity against human leukemia cell lines HL60 and CEM[1]. Tectol is a farnesyltransferase (FTase) inhibitor with IC50s of 2.09 and 1.73 μM for human and T. brucei FTase, respectively. Tectol inhibits drug-resistant strain of P. falciparum (FcB1) with an IC50 of 3.44 μM[1][2].

Molecular Weight

450.53

Formula

C₃₀H₂₆O₄

CAS No.

24449-39-6

SMILES

OC1=C(C=CC=C2)C2=C(O3)C(C=CC3(C)C)=C1C4=C(C=CC5(C)C)C(O5)=C6C(C=CC=C6)=C4O

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

TectolFarnesyl TransferaseParasiteFtasecytotoxicleukemiacelllinesHL60anti-malarialdrug-resistantInhibitorinhibitorinhibit

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