IDO1/TDO-IN-1
IDO1/TDO-IN-1 (30) is a potent dual IDO1 (uncompetitive, Ki of 0.23 μM) and TDO (competitive, Ki of 0.73 μM) inhibitor. IDO1/TDO-IN-1 (30) significantly promotes cell apoptosis through the potential mitochondria-mediated Bcl-2/Bax pathway.
For research use only. We do not sell to patients.
- CAS No.: 2379527-72-5
- Formula: C21H16O6
- Molecular Weight:364.35
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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IDO1 0.23 μM (Ki) |
TDO 0.73 μM (Ki) |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK-293T | IC50 |
>10 μM
Compound: 30
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Cytotoxicity against human HEK-293T cells
Cytotoxicity against human HEK-293T cells
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[PMID: 35358772] |
Chemical Information
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CAS No. 2379527-72-5
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Molecular Weight 364.35
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Formula C21H16O6
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SMILES
CC(OCC1=COC2=C1C(C(C3=C2C=CC4=C3C=CC(C4(C)C)=O)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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