Dresbuxelimab
Based on 1 Customer Validation
Dresbuxelimab (AK-119) is an IgG-κ monoclonal antibody targeting CD73. The expression system is usually CHO (Chinese Hamster Ovary) cells.
For research use only. We do not sell to patients.
- Purity: 98.00%
- CAS No.: 2550560-20-6
- Molecular Weight:146.8 kDa
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Human IgG1 kappa
Human
NT5E/CD73
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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Human IgG1 kappa
ELISA, FACS, Functional assay
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Loaded Dresbuxelimab on AHC2 biosensor, can bind CD73/5'-Nucleotidase Protein, Human (HEK293, His, HY-P70010) with an affinity constant of <1.0E-11 M as determined in BLI assay. -
Flow Cytometry analysis of A431 cells labelling NT5E/CD73 (red) with Dresbuxelimab (anti-NT5E/CD73) (HY-P99865). Goat Anti-Human IgG (Alexa Fluor 488) (HY-P83776) at a dilution of 1/1000 was used as the secondary antibody. Blue-Human IgG1 kappa (HY-P99001). Black-Unlabelled control, cells without incubation with primary antibody.
Chemical Information
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CAS No. 2550560-20-6
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Appearance Liquid
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Molecular Weight 146.8 kDa
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Color Colorless to light yellow
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SMILES
[Dresbuxelimab]
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Synonyms
AK-119
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Shipping
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (253 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
References
[1]. Dresbuxelimab. IMGT.
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)