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AF64394 

Cat. No.: HY-12664 Purity: 98.96%
Handling Instructions

AF64394 is a GPR3 inverse agonist, with a pIC50 of 7.3.

For research use only. We do not sell to patients.

AF64394 Chemical Structure

AF64394 Chemical Structure

CAS No. : 1637300-25-4

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 165 In-stock
Estimated Time of Arrival: December 31
5 mg USD 150 In-stock
Estimated Time of Arrival: December 31
10 mg USD 240 In-stock
Estimated Time of Arrival: December 31
25 mg USD 510 In-stock
Estimated Time of Arrival: December 31
50 mg USD 880 In-stock
Estimated Time of Arrival: December 31
100 mg USD 1500 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Description

AF64394 is a GPR3 inverse agonist, with a pIC50 of 7.3.

IC50 & Target

pIC50: 7.3 (GPR3)[1].

In Vitro

AF64394 is a GPR3 inverse agonist, with a pIC50 of 7.3. AF34394 and related compounds are only of modest potency and are relatively lipophilic (e.g., AF34394 clogP=5.2, LLE=2.1, and 14b clog P=3.1 and LLE=3.2) the series shows promising SAR and represents an excellent start point for further optimization[1].

References
Molecular Weight

393.87

Formula

C₂₁H₂₀ClN₅O

CAS No.

1637300-25-4

SMILES

ClC1=CC(OC(C)C)=C(CNC2=CC(C3=CC=CC=C3)=NC4=NC=NN42)C=C1

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2

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Product Name:
AF64394
Cat. No.:
HY-12664
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AF64394

Cat. No.: HY-12664