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Bobcat339 hydrochloride 

Cat. No.: HY-111558A
Handling Instructions

Bobcat339 hydrochloride is a cytosine-based TET enzyme inhibitor with IC50 of 33 μM (TET1) and 73 μM (TET2). It is useful to the field of epigenetics and serves as a starting point for new therapeutics that target DNA methylation and gene transcription.

For research use only. We do not sell to patients.

Bobcat339 hydrochloride Chemical Structure

Bobcat339 hydrochloride Chemical Structure

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 275 In-stock
Estimated Time of Arrival: December 31
5 mg USD 250 In-stock
Estimated Time of Arrival: December 31
10 mg USD 350 In-stock
Estimated Time of Arrival: December 31
50 mg USD 950 In-stock
Estimated Time of Arrival: December 31
100 mg USD 1500 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

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  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

Bobcat339 hydrochloride is a cytosine-based TET enzyme inhibitor with IC50 of 33 μM (TET1) and 73 μM (TET2). It is useful to the field of epigenetics and serves as a starting point for new therapeutics that target DNA methylation and gene transcription.

IC50 & Target

IC50: 33 μM (TET1), 73 μM (TET1)[1]

Solvent & Solubility
In Vitro: 

DMSO : 130 mg/mL (388.99 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9922 mL 14.9611 mL 29.9222 mL
5 mM 0.5984 mL 2.9922 mL 5.9844 mL
10 mM 0.2992 mL 1.4961 mL 2.9922 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.17 mg/mL (6.49 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.17 mg/mL (6.49 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.17 mg/mL (6.49 mM); Clear solution

References
Molecular Weight

334.20

Formula

C₁₆H₁₃Cl₂N₃O

SMILES

NC1=NC(N(C2=CC=CC(C3=CC=CC=C3)=C2)C=C1Cl)=O.Cl

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Inquiry Information

Product Name:
Bobcat339 hydrochloride
Cat. No.:
HY-111558A
Quantity:

Bobcat339 hydrochloride

Cat. No.: HY-111558A