1. Dye Reagents
  2. DiOC7(3)

DiOC7(3) (Synonyms: 3,3'-Diheptyloxacarbocyanine iodide)

Cat. No.: HY-D1073
Handling Instructions

DiOC7(3) (3,3'-Diheptyloxacarbocyanine iodide) is a green membrane potential probe (Ex=450-490 nm, Em=510-520 nm). DiOC7(3) can be used to quantify the vascular densities.

For research use only. We do not sell to patients.

DiOC7(3) Chemical Structure

DiOC7(3) Chemical Structure

CAS No. : 53213-83-5

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Description

DiOC7(3) (3,3'-Diheptyloxacarbocyanine iodide) is a green membrane potential probe (Ex=450-490 nm, Em=510-520 nm). DiOC7(3) can be used to quantify the vascular densities[1].

In Vivo

Identification for tumour vasculature (frozen section):
Guidelines (Following is our recommended protocol. This protocol only provides a guideline, and should be modified according to your specific needs)[1].
1. The dye is administered to murine via lateral tail vein injection at a dose of 1 mg/kg/ in 50 μL volume.
2. Animals are killed 5 min after dye administration, and tumors are immediately excised and frozen at - 20°C.
3. Frozen sections 10 μm in thickness are rewarmed to room temperature, allowed to air dry.
4. Image using a microscope with 100W mercury lamp illumination and an epifluorescence condenser (excited at 430-490 nm, emitted at 510-520 nm.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

600.57

Formula

C31H41IN2O2

CAS No.
SMILES

CCCCCCCN1/C(OC2=CC=CC=C12)=C/C=C/C3=[N+](CCCCCCC)C4=CC=CC=C4O3.[I-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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DiOC7(3)
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HY-D1073
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