1. Immunology/Inflammation
  2. CD73
  3. CD73-IN-3

CD73-IN-3 

Cat. No.: HY-137246
Handling Instructions

CD73-IN-3 is a potent CD73 inhibitor (IC50=7.3 nM in Calu6 human cell assay). CD73-IN-3, example 2 extracted from patent WO2019168744 A1, has the potential for cancer research.

For research use only. We do not sell to patients.

CD73-IN-3 Chemical Structure

CD73-IN-3 Chemical Structure

CAS No. : 2375815-63-5

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Solution
10 mM * 1 mL in DMSO USD 330 Ask For Quote & Lead Time
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10 mg USD 480 Ask For Quote & Lead Time
25 mg USD 920 Ask For Quote & Lead Time
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Description

CD73-IN-3 is a potent CD73 inhibitor (IC50=7.3 nM in Calu6 human cell assay). CD73-IN-3, example 2 extracted from patent WO2019168744 A1, has the potential for cancer research[1].

In Vitro

CD73-IN-3 inhibits CD73 activity in human serum with an EC50 of 0.213 μM. CD73-IN-3 inhibits CD73 activity in human serum by 56.8%, 71.7% and 76.9% at 0.52 μM, 1.56 μM, 4.68 μM,respectively[1].
In Calu6 human cell assay against CD73, the IC50 for CD73-IN-3 against CD73 is 0.0073 uM[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

286.33

Formula

C₁₅H₁₈N₄O₂

CAS No.
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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CD73-IN-3
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HY-137246
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