1. Metabolic Enzyme/Protease
  2. Drug Metabolite
  3. N-Desmethyl Pimavanserin

N-Desmethyl Pimavanserin (Synonyms: AC-279)

Cat. No.: HY-135392
Handling Instructions

N-Desmethyl Pimavanserin is the active metabolite of Pimavanserin. Pimavanserin is a selective inverse agonist of the 5-HT2A receptor with pIC50 and pKd of 8.73 and 9.3, respectively.

For research use only. We do not sell to patients.

N-Desmethyl Pimavanserin Chemical Structure

N-Desmethyl Pimavanserin Chemical Structure

CAS No. : 639863-77-7

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Description

N-Desmethyl Pimavanserin is the active metabolite of Pimavanserin. Pimavanserin is a selective inverse agonist of the 5-HT2A receptor with pIC50 and pKd of 8.73 and 9.3, respectively.

In Vitro

The mean plasma half-lives for Pimavanserin and its metabolite N-Desmethyl Pimavanserin (AC-279) are 57 hours and 200 hours, respectively.

Molecular Weight

413.53

Formula

C₂₄H₃₂FN₃O₂

CAS No.

639863-77-7

SMILES

O=C(NCC1=CC=C(OCC(C)C)C=C1)N(CC2=CC=C(F)C=C2)C3CCNCC3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

N-Desmethyl PimavanserinAC-279AC279AC 279Drug MetaboliteInhibitorinhibitorinhibit

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