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Results for "

PEG4

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Antibody (1) ADC Linker (164) Androgen Receptor (2) Antibiotic (2) Antibody-Oligonucleotide Conjugates (AOCs) (1) Apoptosis (18) Asialoglycoprotein Receptor (ASGPR) (1) Aurora Kinase (1) Autophagy (15) AUTOTACs (1) Beta-lactamase (1) Biochemical Assay Reagents (68) c-Myc (1) Caspase (1) Dipeptidyl Peptidase (1) DNA Stain (1) DNA/RNA Synthesis (4) Drug Derivative (4) Drug Intermediate (1) Drug-Linker Conjugates for ADC (47) E3 Ligase Ligand-Linker Conjugates (43) Ferroptosis (1) Fluorescent Dye (20) Glutathione Peroxidase (1) HCV (1) HSP (1) Influenza Virus (1) Integrin (4) Isotope-Labeled Compounds (1) JAK (1) Liposome (1) LYTACs (1) MDM-2/p53 (2) Microtubule/Tubulin (12) PARP (1) Phosphoramidites (3) Polo-like Kinase (PLK) (1) PROTAC Linkers (502) PROTACs (2) Radionuclide-Drug Conjugates (RDCs) (8) Reference Standards (4) RIBOTAC (1) SARS-CoV (1) Small Interfering RNA (siRNA) (1) TNF Receptor (1) Topoisomerase (14) VEGFR (1)
By Research Areas:	Cancer (721) Cardiovascular Disease (1) Infection (4) Inflammation/Immunology (6) Neurological Disease (2)
Click Chemistry:	ADC Synthesis (94) TCO (12) Labeling and Fluorescence Imaging (5) DBCO (64) PROTAC Synthesis (174) BCN (13) Azide (114) Tetrazine (42) Alkynes (83)
Oligonucleotides:	Solvents (1) Mouse Pre-designed siRNA Sets (1) Other Phosphoramidite (3) Phosphoramidites (3) siRNAs (1)

849

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Isotope-Labeled Compounds

322

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-126685

*Mal-PEG4-VA-PBD*	Antibiotic Drug-Linker Conjugates for ADC	Cancer
Mal-PEG4-VA-PBD is a agent-linker conjugate for ADC by using the antitumor antibiotic, Pyrrolobenzodiazepine (PBD), linked via Mal-PEG4-VA.

HY-148057

*TCO-PEG4-VC-PAB-MMAE*	Drug-Linker Conjugates for ADC	Cancer
TCO-PEG4-VC-PAB-MMAE is a agent-linker conjugate for ADC. TCO-PEG4-VC-PAB-MMAE contains a cleavable ADC linker (TCO-PEG4-VC-PA) and a potent tubulin inhibitor MMAE (HY-15162) . TCO-PEG4-VC-PAB-MMAE is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.

HY-130435

*DBCO-PEG4-amine*	ADC Linker PROTAC Linkers	Cancer
DBCO-PEG4-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-PEG4-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-PEG4-amine can be used in the synthesis of FPM-PEG4-DBCO (a homobifunctional azide-to-azide cross-linker) . DBCO-PEG4-amine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-158768

*Amino-PEG4-GGFG-Dxd*	Drug-Linker Conjugates for ADC	Cancer
Amino-PEG4-GGFG-Dxd (Compound 13-7) is a drug-linker conjugate for ADC. Amino-PEG4-GGFG-Dxd is composed of Dxd (HY-13631D) and a linker. Amino-PEG4-GGFG-Dxd can be used for synthesis of ADCs

HY-128968

PEG4-aminooxy-MMAF Amberstatin; AS269	Microtubule/Tubulin Drug-Linker Conjugates for ADC	Inflammation/Immunology Cancer
PEG4-aminooxy-MMAF is a agent-linker conjugate for ADC with potent antitumor activity by using the potent antitubulin agent MMAF, linked via the noncleavable PEG4 .

HY-133492

*DBCO-PEG4-MMAF*	Drug-Linker Conjugates for ADC	Cancer
DBCO-PEG4-MMAF is a agent-linker conjugate for ADC with potent antitumor activity by using the tubulin polymerization inhibitor, MMAF, linked via the linker DBCO-PEG4. DBCO-PEG4-MMAF is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-171580

*Mc-PEG4-Val-Ala-PAB-Exatecan*	Drug-Linker Conjugates for ADC Topoisomerase	Cancer
Mc-PEG4-Val-Ala-PAB-Exatecan is a Drug-linker conjugate for ADC. Mc-PEG4-Val-Ala-PAB-Exatecan contains the ADC linker (Mc-PEG4-Val-Ala-PAB) and a DNA topoisomerase I inhibitor Exatecan (HY-13631) .

HY-133433

*DBCO-PEG4-VA-PBD*	Drug-Linker Conjugates for ADC	Cancer
DBCO-PEG4-VA-PBD is a agent-linker conjugate for ADC by using the antitumor antibiotic, Pyrrolobenzodiazepine (PBD), linked via DBCO-PEG4-VA . DBCO-PEG4-VA-PBD is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-159529

*DBCO-PEG4-Eosin 5-isothiocyanate* DBCO-PEG4-Eosin Y	Fluorescent Dye	Others
DBCO-PEG4-Eosin 5-isothiocyanate (DBCO-PEG4-Eosin Y) is a fluorescent probe. DBCO-PEG4-Eosin 5-isothiocyanate contains a clickable functional group, DBCO, and four PEG units. DBCO-PEG4-Eosin 5-isothiocyanate can be used for various imaging detections.

HY-133699

*Pomalidomide-PEG4-COOH*	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-PEG4-COOH is a E3 ligase ligand-linker conjugate. Pomalidomide-PEG4-COOH contains the Pomalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology .

HY-176765

*DBCO-PEG4-VA-PABC-MMAE*	Drug-Linker Conjugates for ADC Microtubule/Tubulin	Cancer
DBCO-PEG4-VA-PABC-MMAE is a drug-linker conjugate for ADC. DBCO-PEG4-VA-PABC-MMAE consists of a tubulin inhibitor (MMAE) (HY-15162) and a cleavable linker (DBCO-PEG4-VA-PABC). DBCO-PEG4-VA-PABC-MMAE can be used for synthesis of ADC ABBV-400 (HY-171945) .

HY-119429

*Bis-PEG4-acid*	PROTAC Linkers	Cancer
Bis-PEG4-acid is a PEG PROTAC linker.

HY-W040214

*m-PEG4-Amine* 1 Publications Verification	ADC Linker PROTAC Linkers	Cancer
m-PEG4-Amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG4-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-130346

*DBCO-PEG4-DBCO*	ADC Linker PROTAC Linkers	Cancer
DBCO-PEG4-DBCO is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-PEG4-DBCO is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-W099536

PEG 4 lauryl ether Tetraoxyethylene glycol monododecyl ether	Biochemical Assay Reagents	Others
PEG-4 lauryl ether is a non-ionic detergent that can be used as an excipient or for the isolation of functional membrane complexes .

HY-W755033

*NH2-PEG4-DOTA*	Biochemical Assay Reagents Radionuclide-Drug Conjugates (RDCs)	Others
NH2-PEG4-DOTA is a bifunctional DOTA chelator with one carboxyl group modified by NH2-PEG4, possessing both a metal-binding domain and a chemically reactive functional group. NH2-PEG4-DOTA can be used for time-resolved fluorescence assays .

HY-141382

*Bromoacetamido-PEG4-acid*	PROTAC Linkers ADC Linker	Cancer
Bromoacetamido-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Bromoacetamido-PEG4-acid is also a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-130591

*Propargyl-PEG4-Br*	ADC Linker PROTAC Linkers	Cancer
Propargyl-PEG4-Br is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG4-Br is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG4-Br is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-130973

*Mal-PEG4-bis-PEG4-propargyl*	ADC Linker	Cancer
Mal-PEG4-bis-PEG4-propargyl is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Mal-PEG4-bis-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-117104

*Hydroxy-PEG4-acid*	ADC Linker PROTAC Linkers	Cancer
Hydroxy-PEG4-acid is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG4-acid is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-140866

*N-(Azido-PEG4)-N-bis(PEG4-NHS ester)*	PROTAC Linkers	Cancer
N-(Azido-PEG4)-N-bis(PEG4-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG4)-N-bis(PEG4-NHS ester) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-145090

*DBCO-N-bis(PEG4-NHS ester)*	PROTAC Linkers ADC Linker	Others
DBCO-N-bis(PEG4-NHS ester) is a PEG linker which contains two PEG4-NHS ester and a DBCO group. DBCO-N-bis(PEG4-NHS ester) is useful for protein modification or labeling. DBCO-N-bis(PEG4-NHS ester) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-120397

Bis-propargyl-PEG4	PROTAC Linkers	Infection Cancer
Bis-propargyl-PEG4 is a *PEG*-based PROTAC linker used in the synthesis of PROTACs. Bis-propargyl-PEG4 is used for the synthesis of demethylvancomycin dimers . Bis-propargyl-PEG4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-151741

*Biotin-PEG4-MeTz*	ADC Linker	Others
Biotin-PEG4-MeTz is a click chemistry reagent containing a terminal methyltetrazine group that reacts with trans-cyclooctene. Biotin-PEG4-MeTz can be used for the preparation of biotinylated conjugates .

HY-116427

*Propargyl-PEG4-thiol*	ADC Linker PROTAC Linkers	Cancer
Propargyl-PEG4-thiol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG4-thiol is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG4-thiol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-140297

*Carboxyrhodamine 110-PEG4-DBCO*	PROTAC Linkers	Cancer
Carboxyrhodamine 110-PEG4-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Carboxyrhodamine 110-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-W190956

*(S,R,S)-AHPC-PEG4-acid*	Others	Cancer
(S,R,S)-AHPC-PEG4-acid is a synthetic PROTAC ligand that binds the E3 ligase ligand to the PEG4 arm, thereby enhancing PROTAC drug research and discovery .

HY-135970

*Alkyne-PEG4-SS-PEG4-alkyne*	ADC Linker	Cancer
Alkyne-PEG4-SS-PEG4-alkyne is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Alkyne-PEG4-SS-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-140114

*Acid-PEG4-S-S-PEG4-acid*	PROTAC Linkers	Cancer
Acid-PEG4-S-S-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-177685

*N-(TCO-PEG4)-N-(PEG4-Val-Cit-PAB-MMAE)-N-(PEG4-Val-Cit-PAB-Exatecan)*	Drug-Linker Conjugates for ADC Topoisomerase Microtubule/Tubulin	Cancer
N-(TCO-PEG4)-N-(PEG4-Val-Cit-PAB-MMAE)-N-(PEG4-Val-Cit-PAB-Exatecan) is a drug-linker conjugate for ADC (Drug-Linker Conjugate for ADC), consisting of a tubulin polymerization inhibitor MMAE (HY-15162) and a DNA topoisomerase I inhibitor Exatecan (HY-13631), and an ADC linker composition. N-(TCO-PEG4)-N-(PEG4-Val-Cit-PAB-MMAE)-N-(PEG4-Val-Cit-PAB-Exatecan) can be used for synthesis of ADCs and for cancer research.

HY-177684

*N-(endo-BCN-PEG4)-N-(PEG4-Val-Cit-PAB-MMAE)-N-(PEG4-Val-Cit-PAB-Exatecan)*	Drug-Linker Conjugates for ADC Topoisomerase Microtubule/Tubulin	Cancer
N-(endo-BCN-PEG4)-N-(PEG4-Val-Cit-PAB-MMAE)-N-(PEG4-Val-Cit-PAB-Exatecan) is a drug-linker conjugate for ADC (Drug-Linker Conjugate for ADC), consisting of a tubulin polymerization inhibitor MMAE (HY-15162) and a DNA topoisomerase I inhibitor Exatecan (HY-13631), and an ADC linker composition. N-(endo-BCN-PEG4)-N-(PEG4-Val-Cit-PAB-MMAE)-N-(PEG4-Val-Cit-PAB-Exatecan) can be used for synthesis of ADCs and for cancer research.

HY-140532

*N-(Amino-PEG4)-N-Biotin-PEG4-acid*	PROTAC Linkers	Cancer
N-(Amino-PEG4)-N-Biotin-PEG4-acid is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-141071

*N-(m-PEG4)-N'-(DBCO-PEG4)-Cy5*	PROTAC Linkers	Cancer
N-(m-PEG4)-N'-(DBCO-PEG4)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(m-PEG4)-N'-(DBCO-PEG4)-Cy5 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-126669

*Mal-PEG4-VA*	ADC Linker	Cancer
Mal-PEG4-VA is a cleavable ADC linker containing a Maleimide group. Mal-PEG4-VA is used for making antibody-drug conjugate.

HY-W800668

*(S,R,S)-AHPC-PEG4-NHS ester*	PROTAC Linkers	Cancer
(S, R, S)-AHPC-PEG4-NHS ester is a PROTAC linker that incorporatess an E3 ligase ligand with a PEG4 spacer to empower PROTAC medicine chemistry. It is is reactive with amine molecule. PEG4 arm increases the molecule's solubility.

HY-126496

PEG4-SPDP	ADC Linker	Cancer
PEG4-SPDP is a cleavable ADC linker used for the antibody-drug conjugates (ADCs).

HY-140388

PEG4-MS	PROTAC Linkers	Cancer
PEG4-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-133009

*BCN-PEG4-acid*	PROTAC Linkers	Cancer
BCN-PEG4-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. BCN-PEG4-acid contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-140310

*TCO-PEG4-DBCO*	ADC Linker PROTAC Linkers	Cancer
TCO-PEG4-DBCO is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. TCO-PEG4-DBCO is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . TCO-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. TCO-PEG4-DBCO also contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.

HY-130387

*Propargyl-PEG4-Tos*	PROTAC Linkers ADC Linker	Cancer
Propargyl-PEG4-Tos is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG4-Tos is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG4-Tos is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-140599

*Propargyl-PEG4-S-PEG4-Boc*	PROTAC Linkers	Cancer
Propargyl-PEG4-S-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG4-S-PEG4-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-140131

*Biotin-PEG4-PC-PEG4-alkyne*	PROTAC Linkers	Cancer
Biotin-PEG4-PC-PEG4-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG4-PC-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-141124

*NHS-PEG4-(m-PEG4)3-ester*	PROTAC Linkers	Cancer
NHS-PEG4-(m-PEG4)3-ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-130312

*N-(Azido-PEG4)-N-Boc-PEG4-NHS ester*	PROTAC Linkers	Cancer
N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is a *PEG*-based PROTAC linker with a terminal azide group. N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is used in the synthesis of PROTACs N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-140582

*N-(DBCO-PEG4)-N-Biotin-PEG4-NHS*	PROTAC Linkers	Cancer
N-(DBCO-PEG4)-N-Biotin-PEG4-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(DBCO-PEG4)-N-Biotin-PEG4-NHS is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-177683

*N-(DBCO-PEG4)-N-(PEG4-Val-Cit-PAB-MMAE)-N-(PEG4-Val-Cit-PAB-Exatecan)*	Drug-Linker Conjugates for ADC Topoisomerase Microtubule/Tubulin	Cancer
N-(DBCO-PEG4)-N-(PEG4-Val-Cit-PAB-MMAE)-N-(PEG4-Val-Cit-PAB-Exatecan) is a drug-linker conjugate for ADC (Drug-Linker Conjugate for ADC), consisting of a tubulin polymerization inhibitor MMAE (HY-15162) and a DNA topoisomerase I inhibitor Exatecan (HY-13631), and an ADC linker composition. N-(DBCO-PEG4)-N-(PEG4-Val-Cit-PAB-MMAE)-N-(PEG4-Val-Cit-PAB-Exatecan) can be used for synthesis of ADCs and for cancer research.

HY-177686

*N-(Azido-PEG4)-N-(PEG4-Val-Cit-PAB-MMAF)-N-(PEG4-Val-Cit-PAB-Exatecan)*	Drug-Linker Conjugates for ADC Topoisomerase Microtubule/Tubulin	Cancer
N-(Azido-PEG4)-N-(PEG4-Val-Cit-PAB-MMAF)-N-(PEG4-Val-Cit-PAB-Exatecan) is a drug-linker conjugate for ADC (Drug-Linker Conjugate for ADC), consisting of a tubulin polymerization inhibitor MMAE (HY-15162) and a DNA topoisomerase I inhibitor Exatecan (HY-13631), and an ADC linker composition. N-(Azido-PEG4)-N-(PEG4-Val-Cit-PAB-MMAF)-N-(PEG4-Val-Cit-PAB-Exatecan) can be used for synthesis of ADCs and for cancer research.

HY-177687

*N-(Mal-PEG4)-N-(PEG4-Val-Cit-PAB-MMAF)-N-(PEG4-Val-Cit-PAB-Exatecan)*	Drug-Linker Conjugates for ADC Topoisomerase Microtubule/Tubulin	Cancer
N-(Mal-PEG4)-N-(PEG4-Val-Cit-PAB-MMAF)-N-(PEG4-Val-Cit-PAB-Exatecan) is a drug-linker conjugate for ADC (Drug-Linker Conjugate for ADC), consisting of a tubulin polymerization inhibitor MMAE (HY-15162) and a DNA topoisomerase I inhibitor Exatecan (HY-13631), and an ADC linker composition. N-(Mal-PEG4)-N-(PEG4-Val-Cit-PAB-MMAF)-N-(PEG4-Val-Cit-PAB-Exatecan) can be used for synthesis of ADCs and for cancer research.

HY-177682

*N-(NHS-PEG4)-N-(PEG4-Val-Cit-PAB-MMAE)-N-(PEG4-Val-Cit-PAB-Exatecan)*	Drug-Linker Conjugates for ADC Topoisomerase Microtubule/Tubulin	Cancer
N-(NHS-PEG4)-N-(PEG4-Val-Cit-PAB-MMAE)-N-(PEG4-Val-Cit-PAB-Exatecan) is a drug-linker conjugate for ADC (Drug-Linker Conjugate for ADC), consisting of a tubulin polymerization inhibitor MMAE (HY-15162) and a DNA topoisomerase I inhibitor Exatecan (HY-13631), and an ADC linker composition. N-(NHS-PEG4)-N-(PEG4-Val-Cit-PAB-MMAE)-N-(PEG4-Val-Cit-PAB-Exatecan) can be used for synthesis of ADCs and for cancer research.

HY-177688

*N-(NHS-PEG4)-N-(PEG4-Val-Cit-PAB-MMAF)-N-(PEG4-Val-Cit-PAB-Exatecan)*	Drug-Linker Conjugates for ADC Topoisomerase Microtubule/Tubulin	Cancer
N-(NHS-PEG4)-N-(PEG4-Val-Cit-PAB-MMAF)-N-(PEG4-Val-Cit-PAB-Exatecan) is a drug-linker conjugate for ADC (Drug-Linker Conjugate for ADC), consisting of a tubulin polymerization inhibitor MMAE (HY-15162) and a DNA topoisomerase I inhibitor Exatecan (HY-13631), and an ADC linker composition. N-(NHS-PEG4)-N-(PEG4-Val-Cit-PAB-MMAF)-N-(PEG4-Val-Cit-PAB-Exatecan) can be used for synthesis of ADCs and for cancer research.

Cat. No.	Product Name	Type

HY-159529

*DBCO-PEG4-Eosin 5-isothiocyanate* DBCO-PEG4-Eosin Y	Fluorescent Dye
DBCO-PEG4-Eosin 5-isothiocyanate (DBCO-PEG4-Eosin Y) is a fluorescent probe. DBCO-PEG4-Eosin 5-isothiocyanate contains a clickable functional group, DBCO, and four PEG units. DBCO-PEG4-Eosin 5-isothiocyanate can be used for various imaging detections.

HY-D2329

*Fluorescein-PEG4-NHS ester*	Fluorescent Dye
Fluorescein-PEG4-NHS ester is a colorimetric probe formed by the reaction of adipic dihydrazide and fluorescein isothiocyanate .

HY-145383

Biotin-PEG4-dialkoxydiphenylsilane-picolyl azide

Fluorescent Dye

Biotin-PEG4-dialkoxydiphenylsilane-picolyl azide is a clickable, acid-cleavable biotin-picolyl azide. Biotin-PEG4-dialkoxydiphenylsilane-picolyl azide is an enrichment handle of cell surface glycoproteins for protein labeling . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-D2527

*Biotin-PEG4-amide-PEG2-C6-Cl*	Fluorescent Dye
Biotin-PEG4-amide-PEG2-C6-Cl is a biotinylated PEG4-amide-PEG2-C6-Cl.

HY-D2413

BODIPY FL VH032

BODIPY FL PEG4-VH032

Fluorescent Dye

BODIPY FL VH032 is a high-affinity VHL fluorescent probe with a K_d value of 3.01 nM. BODIPY FL VH032 consists of von Hippel-Lindau (VHL) ligand VH032 (HY-120217) and BODIPY FL (HY-43520). BODIPY FL VH032 can be used for time-resolved fluorescence resonance energy transfer (TR-FRET) detection for high-throughput identification and characterization of VHL ligands with maximum excitation emission wavelength: 504/520 nm .

HY-D2106

*TAMRA-PEG4-NHS*	Fluorescent Dye
TAMRA-PEG4-NHS is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG4-NHS contains NHS groups that react with ammonia to form ester bonds.

HY-D2109

*TAMRA-PEG4-COOH*	Fluorescent Dye
TAMRA-PEG4-COOH is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG4-COOH contains carboxyl groups, which can condense ammonia to form covalent bonds.

HY-D2140

*Cy3-PEG4-Alkyne*	Fluorescent Dye
Cy3-PEG4-Alkyne is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 4 PEG units. Cy3-PEG4-Alkyne contains Alkyne groups and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-D2117

*TAMRA-PEG4-Me-Tet*	Fluorescent Dye
TAMRA-PEG4-Me-Tet is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG8-Me-Tet contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

HY-172717

*TAMRA-PEG4-t-butyl ester*	Fluorescent Dye
TAMRA-PEG4-t-butyl ester is a TAMRA red-fluorescent dye linker, with excitation/emission maximum 553/575 nm, containing a t-butyl protected carboxyl group which can be deprotected under acidic conditions.

HY-W190940

*Biotin-PEG4-S-S-acid*	Fluorescent Dye
Biotin-PEG4-S-S-acid is a cleavable reagent which can efficiently introduce a biotin moiety to amine-containing biomolecules. The disulfide bond in this linker can be cleaved using reducing agents such as DTT, BME and TCEP to remove the biotin label.

HY-D3264

*SiR-PEG4-DBCO*	Fluorescent Dye
SiR-PEG4-DBCO is a novel fluorescent labeling molecule that combines the superior fluorescent properties of silicon-rhodamine dyes with the functionalities of polyethylene glycol (PEG) and Click Chemistry. SiR dyes exhibit excellent photostability under identical excitation conditions, making them suitable for long-term cellular imaging (Ex = 640 nm, Em = 670–680 nm).

HY-D2845C

*4-arm-PEG20000-FITC*	Fluorescent Dye
4-arm-PEG20000-FITC is a fluorescent dye composed of FITC (HY-66019) and four-arm polyethylene glycol (4-Arm PEG). 4-arm-PEG20000-FITC can be used to modify proteins, peptides and other materials with active groups (Ex/Em=488/525 nm) .

HY-D3340

*AMCA-PEG4-acid*	Fluorescent Dye

HY-D3343

*AMCA-PEG4-amine*	Fluorescent Dye

HY-D3341

*AMCA-PEG4-NHS ester*	Fluorescent Dye

HY-D3344

*AMCA-PEG4-propargyl*	Fluorescent Dye

HY-D3338

*AMCA-PEG4-azide*	Fluorescent Dye

HY-D3342

*AMCA-PEG4-Mal*	Fluorescent Dye

HY-D3339

*AMCA-PEG4-DBCO*	Fluorescent Dye

Cat. No.	Product Name	Type

HY-W190908A

*Desthiobiotin-PEG4-NHS ester*	Biochemical Assay Reagents
Desthiobiotin-PEG4-NHS ester is a PEG derivative composed of desthiobiotin, 4 PEG units, and NHS ester. NHS ester can be conjugated to amino acids or other molecules containing amino groups.

HY-W190984

*Desthiobiotin-PEG4-alkyne*	Biochemical Assay Reagents
Desthiobiotin-PEG4-alkyne is a biotinylated biochemical reagent, which can be utilized in conjunction with click chemistry for the selective labeling and enrichment of certain tRNAs .

HY-174914

*Biotin-PEG4-mal*	Biochemical Assay Reagents
Biotin-PEG4-mal is a PEG derivative composed of Biotin, 4 PEG units and Maleimide. Biotin can form a stable non-covalent bond with streptavidin.

HY-W190755

*Mal-PEG4-mal*	Biochemical Assay Reagents
Mal-PEG4-Mal is a PEG derivative with maleimide groups at both ends. Maleimide is a functional group that can undergo Michael addition reactions with sulfhydryl groups (–SH) and can be used for bioconjugation .

HY-W879032

*Endo-BCN-PEG4-Pomalidomide*	Biochemical Assay Reagents
Endo-BCN-PEG4-Pomalidomide is a PEG derivative composed of BCN, PEG4 and Pomalidomide (HY-10984). The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc .

HY-W879031

*Endo-BCN-PEG4-Palmitic*	Biochemical Assay Reagents
Endo-BCN-PEG4-Palmitic is a PEG derivative containing an endo-BCN cycloalkyne structure, a tetraethylene glycol (PEG4) linker, and a Palmitic acid (HY-N0830) fatty acid group. Endo-BCN-PEG4-Palmitic can be used for drug delivery, surface modification, and click chemistry reactions .

HY-W190741

*NH2-PEG4-COOMe*	Biochemical Assay Reagents
NH2-PEG4-COOMe is a biochemical reagent that can be used in drug delivery research .

HY-W796277

Dde Biotin-PEG4	Biochemical Assay Reagents
Dde Biotin-PEG4 is a PEG derivative composed of Biotin, 5 PEG units, and Dde protecting group. Biotin can form a stable non-covalent bond with streptavidin.

HY-174897

*DSPE-PEG4-NHS ester*	Biochemical Assay Reagents
DSPE-PEG4-NHS ester is a lipid-containing PEG derivative that can be used to form micelles as nanoparticles for drug delivery . NHS esters can be conjugated to amino acids or other molecules containing an amino group.

HY-174917

*Biotin-PEG4-Acrylamide*	Biochemical Assay Reagents
Biotin-PEG Acrylamide is a PEG derivative composed of Biotin, 4 PEG units and Acrylamide. Biotin can form a stable non-covalent bond with streptavidin.

HY-174904

*Dde Biotin-PEG4-COOH*	Biochemical Assay Reagents
Dde Biotin-PEG4-COOH is a PEG derivative composed of Biotin, 5 PEG units, and a carboxyl group (-COOH). Biotin can form a stable non-covalent bond with streptavidin. The carboxyl group can easily form a stable amide bond with the amino group, and can also form an ester bond with the hydroxyl group.

HY-W096120C

Azide-PEG4-Desthiobiotin

Biochemical Assay Reagents

Azide-PEG4-Desthiobiotin is a PEG derivative consisting of desthiobiotin, 4 PEG unit, and an azide group. Biotin can form a stable non-covalent bond with streptavidin. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-driven alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups .

Cat. No.	Product Name	Target	Research Area

HY-P11026

DOTA-TMVP1446 DOTA-PEG4-TMVP1446	VEGFR	Cancer
DOTA-TMVP1446 is a VEGFR-3 targeting peptide. DOTA-TMVP1446 labeled with ⁶⁸Ga accurately detectes the status of lymph node metastasis, even in micrometastatic tumors, in the B16-F10 tumor mice model. DOTA-TMVP1446 can be used as a radiotracer for cancer-metastatic sentinel lymph nodes (m-SLN) imaging .

HY-P10590

Talogreptide mesaroxetan	Fluorescent Dye	Cancer
Talogreptide mesaroxetan is a diagnostic imaging agent, with antineoplastic effect .

HY-P10906

Talovirtide	Biochemical Assay Reagents	Others
Talovirtide is a peptide containing L-valyl .

HY-P10872

P315V3	SARS-CoV	Infection
P315V3 is an pan inhibitor for coronavirus, that inhibits SARS-CoV-2 prototypePT, Delta, BA.1 and BA.4 strain with IC₅₀s of 10.9, 8.9, 8.6, and 2.7 nM. P315V3 exhibits cytotoxicity in Vero cell with CC₅₀ of 4.3 μM. P315V3 exhibits anti-infectious efficacy in mouse models .

HY-179583

*FSC(PEG4-αvβ6)₃*	Integrin	Cancer
FSC(PEG4-avb6)₃ is a tracer targeting αvβ6 integrin trimer (IC₅₀ = 0.69 nM). FSC(PEG4-avb6)₃ can be used for the study of head-and-neck, lung, breast, and pancreatic carcinomas .

HY-P11455

Lipopeptide CPE4	Liposome	Others
Lipopeptide CPE4 is a PEG-modified peptide E4 [(EIAALEK) ⁴]. Lipopeptide CPE4 is capable of coiled-coil formation when attached to liposomes. Lipopeptide CPE4 triggers membrane fusion between liposomes and living cells with concomitant efficient cytosolic delivery of a variety of compounds such as fluorescent dyes Propidium Iodide (PI) (HY-D0815) and TO-PRO-3 iodide (HY-117070), and Doxorubicin (DOX) (HY-15142A). Lipopeptide CPE4 can be used for drug delivery research .

HY-P11773

3P-RGD2	Radionuclide-Drug Conjugates (RDCs) Integrin	Others
3P-RGD2 is a dimeric cyclic RGD (Arg-Gly-Asp) peptide. When radiolabeled with ^99mTc, 3P-RGD2 serves as a selective radiotracer for integrin α_vβ₃. When radiolabeled with ^99mTc, 3P-RGD2 enables single-photon emission computed tomography imaging of integrin α_vβ₃ .

HY-P11774

HYNIC-3P-RGD2	Integrin	Cancer
HYNIC-3P-RGD2 is a dimeric cyclic RGD peptide with high binding affinity for integrin α_vβ₃ (IC₅₀ = 33 nM). HYNIC-3P-RGD2 acts as a precursor molecule for radiotracers and is used to detect tumor angiogenesis .

Cat. No.	Product Name	Target	Research Area	Image

HY-P991930

ARX305 Antibody	ADC Antibody TNF Receptor	Cancer
ARX305 Antibody is an anti-human CD70 antibody. ARX305 Antibody can generate antibody drug conjugate (ADC) (ARX305) with a potent microtubule inhibitor PEG4-aminooxy-MMAF (AS269) (HY-128968). ARX305 Antibody can be used for the study of multiple solid and hematological cancers .

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