Tetrazine-diazo-PEG4-biotin
Tetrazine-diazo-PEG4-biotin is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Tetrazine-diazo-PEG4-biotin is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
For research use only. We do not sell to patients.
- Formula: C45H57N11O9S
- Molecular Weight:928.07
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cleavable Linker |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 928.07
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Formula C45H57N11O9S
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SMILES
OC(C(/N=N/C1=CC=C(C(NCC2=CC=C(C3=NN=CN=N3)C=C2)=O)C=C1)=C4)=CC=C4CCNC(CCOCCOCCOCCOCCNC(CCCC[C@H]5[C@@H](NC(N6)=O)[C@@H]6CS5)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)