Cl-PEG4-acid
Based on 1 Customer Validation
Cl-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 158553-98-1
- Formula: C10H19ClO6
- Molecular Weight:270.71
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Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All PROTAC Linkers Isoforms
More
Biological Activity
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 158553-98-1
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Appearance Liquid (Density: 1.202 g/cm3)
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Molecular Weight 270.71
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Formula C10H19ClO6
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Color Colorless to light yellow
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SMILES
OC(COCCOCCOCCOCCCl)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : ≥ 200 mg/mL (738.80 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.6940 mL | 18.4699 mL | 36.9399 mL | 92.3497 mL |
| 5 mM | 0.7388 mL | 3.6940 mL | 7.3880 mL | 18.4699 mL | |
| 10 mM | 0.3694 mL | 1.8470 mL | 3.6940 mL | 9.2350 mL | |
| 15 mM | 0.2463 mL | 1.2313 mL | 2.4627 mL | 6.1566 mL | |
| 20 mM | 0.1847 mL | 0.9235 mL | 1.8470 mL | 4.6175 mL | |
| 25 mM | 0.1478 mL | 0.7388 mL | 1.4776 mL | 3.6940 mL | |
| 30 mM | 0.1231 mL | 0.6157 mL | 1.2313 mL | 3.0783 mL | |
| 40 mM | 0.0923 mL | 0.4617 mL | 0.9235 mL | 2.3087 mL | |
| 50 mM | 0.0739 mL | 0.3694 mL | 0.7388 mL | 1.8470 mL | |
| 60 mM | 0.0616 mL | 0.3078 mL | 0.6157 mL | 1.5392 mL | |
| 80 mM | 0.0462 mL | 0.2309 mL | 0.4617 mL | 1.1544 mL | |
| 100 mM | 0.0369 mL | 0.1847 mL | 0.3694 mL | 0.9235 mL |
Cl-PEG4-acid Related Classifications
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