1. PROTAC
  2. E3 Ligase Ligand-Linker Conjugate
  3. Nutlin-C1-amido-PEG4-C2-N3

Nutlin-C1-amido-PEG4-C2-N3 (Synonyms: MDM2 Ligand-Linker Conjugates 1; E3 ligase Ligand-Linker Conjugates 48)

Cat. No.: HY-128832
Handling Instructions

Nutlin-C1-amido-PEG4-C2-N3 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Nutlin 3 based MDM2 ligand and 4-unit PEG linker used in PROTAC technology.

For research use only. We do not sell to patients.

Nutlin-C1-amido-PEG4-C2-N3 Chemical Structure

Nutlin-C1-amido-PEG4-C2-N3 Chemical Structure

Size Stock
100 mg Get quote
500 mg Get quote
1 g Get quote
2 g Get quote

* Please select Quantity before adding items.

Top Publications Citing Use of Products

View All E3 Ligase Ligand-Linker Conjugate Isoform Specific Products:

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Nutlin-C1-amido-PEG4-C2-N3 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Nutlin 3 based MDM2 ligand and 4-unit PEG linker used in PROTAC technology.

IC50 & Target[1]

MDM2

 

Molecular Weight

883.82

Formula

C₄₂H₅₂Cl₂N₈O₉

SMILES

O=C(CN(C(N1C(C2=CC=C(OC)C=C2OC(C)C)=N[[email protected]](C3=CC=C(Cl)C=C3)[[email protected]@H]1C4=CC=C(Cl)C=C4)=O)CC5)N5CC(NCCOCCOCCOCCOCCN=[N+]=[N-])=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Nutlin-C1-amido-PEG4-C2-N3MDM2 Ligand-Linker Conjugates 1E3 ligase Ligand-Linker Conjugates 48E3 Ligase Ligand-Linker ConjugateInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product name

 

Salutation

Applicant name *

 

Email address *

Phone number *

 

Organization name *

Country or Region *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product name:
Nutlin-C1-amido-PEG4-C2-N3
Cat. No.:
HY-128832
Quantity:
MCE Japan Authorized Agent: