BG-PEG4-Amine
Based on 1 Customer Validation
BG-PEG4-Amine is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 98.01%
- Formula: C24H35N7O6
- Molecular Weight:517.58
-
Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
All PROTAC Linkers Isoforms
More
Biological Activity
PROTACs contain two different ligands connected by a linker; one is a ligand for an E1122 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
Appearance Solid
-
Molecular Weight 517.58
-
Formula C24H35N7O6
-
Color White to off-white
-
SMILES
NCCOCCOCCOCCOCCC(NCC1=CC=C(C=C1)COC2=C3NC=NC3=NC(N)=N2)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (193.21 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (238 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.9321 mL | 9.6603 mL | 19.3207 mL | 48.3017 mL |
| 5 mM | 0.3864 mL | 1.9321 mL | 3.8641 mL | 9.6603 mL | |
| 10 mM | 0.1932 mL | 0.9660 mL | 1.9321 mL | 4.8302 mL | |
| 15 mM | 0.1288 mL | 0.6440 mL | 1.2880 mL | 3.2201 mL | |
| 20 mM | 0.0966 mL | 0.4830 mL | 0.9660 mL | 2.4151 mL | |
| 25 mM | 0.0773 mL | 0.3864 mL | 0.7728 mL | 1.9321 mL | |
| 30 mM | 0.0644 mL | 0.3220 mL | 0.6440 mL | 1.6101 mL | |
| 40 mM | 0.0483 mL | 0.2415 mL | 0.4830 mL | 1.2075 mL | |
| 50 mM | 0.0386 mL | 0.1932 mL | 0.3864 mL | 0.9660 mL | |
| 60 mM | 0.0322 mL | 0.1610 mL | 0.3220 mL | 0.8050 mL | |
| 80 mM | 0.0242 mL | 0.1208 mL | 0.2415 mL | 0.6038 mL | |
| 100 mM | 0.0193 mL | 0.0966 mL | 0.1932 mL | 0.4830 mL |