FmocNH-PEG4-t-butyl ester

Name: FmocNH-PEG4-t-butyl ester
Brand: MedChemExpress
SKU: HY-132064
Rating: 4.5 (0 reviews)

Cat. No.: HY-132064: Ficha de datos
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FmocNH-PEG4-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Para uso exclusivo en investigación. No vendemos a pacientes.

FmocNH-PEG4-t-butyl ester Estructura química

No. CAS : 2148295-94-5

Tamaño	Stock	Cantidad
250 mg	En stock	Estimated Time of Arrival: December 31
500 mg	En stock	Estimated Time of Arrival: December 31
1 g	En stock	Estimated Time of Arrival: December 31
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10 g	Obtener un presupuesto

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Revisión del cliente

Based on 1 Customer Validation

Recomendaciones destacadas

•Related Small Molecules:

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Ver todos los productos específicos de isoformas PROTAC Linkers:

Ver todas las isoformas

PEG Linkers Alkyl-Chain Linkers Alkyl/ether Linkers

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Pureza y Documentación
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Revisión del cliente

Descripciòn

FmocNH-PEG4-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs^[1].

IC₅₀ & Target

PEGs

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Peso molecular

543.65

Fòrmula

C₃₀H₄₁NO₈

No. CAS

2148295-94-5

Appearance

Liquid (Density: 1.145 g/cm³)

Color

Colorless to light yellow

SMILES

O=C(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)NCCOCCOCCOCCOCCC(OC(C)(C)C)=O

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Pureza y Documentación

Purity: ≥97.0%

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Ficha de datos (263 KB) SDS (393 KB)

COA (243 KB) HNMR (136 KB) LCMS (261 KB)

Instrucciones de manejo (2659 KB)

Referencias

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 [Content Brief]