country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-W800686

Copy Link Print Information

Acid-PEG4-NHS ester

Customer Review

Based on 1 Customer Validation

Acid-PEG4-NHS ester is a PEG4-based PROTAC linker that can be used for the synthesis of PROTACs. Acid-PEG4-NHS ester contains a carboxylic acid and an NHS ester; the carboxylic acid reacts with primary amines in the presence of activators such as EDC or HATU, while the NHS ester also reacts with primary amines, enabling PEGylation and bioconjugation of primary amine-containing molecules.

For research use only. We do not sell to patients.

Purity: 95.0%
CAS No.: 2639395-41-6
Formula: C₁₆H₂₅NO₁₀
Molecular Weight:391.37

Storage:

-20°C, protect from light, stored under nitrogen

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Acid-PEG4-NHS ester Chemical Structure

CAS No.: 2639395-41-6

Size

Price

Stock

Quantity

Amount: USD 0.00

* Please select Quantity before adding items.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

All PROTAC Linkers Isoforms :

In Vitro

Acid-PEG4-NHS ester reacts with primary amines through its carboxylic acid group in the presence of activators such as EDC or HATU, while its NHS ester group also reacts with primary amines, enabling PEGylation, bioconjugation, and construction of PROTAC molecules.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2639395-41-6
Appearance Solid
Molecular Weight 391.37
Formula C₁₆H₂₅NO₁₀
Color White to off-white
SMILES

O=C(CCOCCOCCOCCOCCC(ON1C(CCC1=O)=O)=O)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light, stored under nitrogen

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)