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Cat. No.: HY-182972

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Mal-PEG4-NPV-PABC-DMEDA-tofacitinib

Mal-PEG4-NPV-PABC-DMEDA-tofacitinib is a conjugate of a toxin and a linker, consisting of the JAK inhibitor Tofacitinib (HY-40354) and the linker Mal-PEG4-NPV-PABC-DMEDA (HY-182977). Mal-PEG4-NPV-PABC-DMEDA-tofacitinib can be used for the synthesis of ADC molecules.

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CAS No.: 3110422-32-4
Formule: C₅₈H₈₀N₁₄O₁₅
Masse moléculaire:1213.34

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Please store the product under the recommended conditions in the Certificate of Analysis.

Mal-PEG4-NPV-PABC-DMEDA-tofacitinib Chemical Structure

CAS No.: 3110422-32-4

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Voir tous les produits spécifiques à Isoform Drug-Linker Conjugates for ADC :

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Chemical Information

CAS No. 3110422-32-4
Masse moléculaire 1213.34
Formule C₅₈H₈₀N₁₄O₁₅
SMILES

O=C(N1C2=NC=NC(N([C@@H](C3)[C@@H](CCN3C(CC#N)=O)C)C)=C2C=C1)N(CCN(C)C(OCC4=CC=C(NC([C@H](C(C)C)NC([C@@H]5CCCN5C([C@@H](NC(CCOCCOCCOCCOCCN6C(C=CC6=O)=O)=O)CC(N)=O)=O)=O)=O)C=C4)=O)C
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Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Murray E, et al. A Rationally Designed Novel Bifunctional Human TNF-α- and Janus Kinase-Targeted soloMER Drug Conjugate (SDC) with a Neutrophil Elastase Cleavable Linker Delivering Inflammation Site-Specific Release of Payload. J Med Chem. 2026 Apr 7. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Mal-PEG4-NPV-PABC-DMEDA-tofacitinib

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Mal-PEG4-NPV-PABC-DMEDA-tofacitinib

Voir tous les produits spécifiques à Isoform Drug-Linker Conjugates for ADC

Voir tous les produits spécifiques à Isoform JAK

Activité biologique

Description

Chemical Information

Pureté et documentation

Références

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Mal-PEG4-NPV-PABC-DMEDA-tofacitinib Related Classifications

HY-182972 Related Classifications

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