1. Cytoskeleton
    Cell Cycle/DNA Damage
    Antibody-drug Conjugate/ADC Related
  2. Microtubule/Tubulin
    Drug-Linker Conjugates for ADC
  3. PEG4-aminooxy-MMAF

PEG4-aminooxy-MMAF 

Cat. No.: HY-128968 Purity: 97.20%
Handling Instructions

PEG4-aminooxy-MMAF is a drug-linker conjugate for ADC with potent antitumor activity by using the potent antitubulin agent MMAF, linked via the noncleavable PEG4.

For research use only. We do not sell to patients.

PEG4-aminooxy-MMAF Chemical Structure

PEG4-aminooxy-MMAF Chemical Structure

CAS No. : 1415246-35-3

Size Price Stock Quantity
5 mg USD 995 In-stock
Estimated Time of Arrival: December 31
10 mg USD 1450 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
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Description

PEG4-aminooxy-MMAF is a drug-linker conjugate for ADC with potent antitumor activity by using the potent antitubulin agent MMAF, linked via the noncleavable PEG4[1].

IC50 & Target

Auristatin

 

Molecular Weight

923.19

Formula

C₄₇H₈₂N₆O₁₂

CAS No.

1415246-35-3

SMILES

OC([[email protected]](CC1=CC=CC=C1)NC([[email protected]](C)[[email protected]]([[email protected]@]2([H])N(CCC2)C(C[[email protected]@H](OC)[[email protected]]([[email protected]@H](C)CC)N(C)C([[email protected]](C(C)C)NC([[email protected]](C(C)C)N(C)CCOCCOCCOCCON)=O)=O)=O)OC)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (108.32 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.0832 mL 5.4160 mL 10.8320 mL
5 mM 0.2166 mL 1.0832 mL 2.1664 mL
10 mM 0.1083 mL 0.5416 mL 1.0832 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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Keywords:

PEG4-aminooxy-MMAFMicrotubule/TubulinDrug-Linker Conjugates for ADCInhibitorinhibitorinhibit

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Product Name:
PEG4-aminooxy-MMAF
Cat. No.:
HY-128968
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