2. Antibody-drug Conjugate/ADC Related
  3. ADC Linker
  4. PC Alkyne-PEG4-NHS ester

PC Alkyne-PEG4-NHS ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). PC Alkyne-PEG4-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

For research use only. We do not sell to patients.

PC Alkyne-PEG4-NHS ester Chemical Structure

PC Alkyne-PEG4-NHS ester Chemical Structure

CAS No. : 1802907-98-7

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50 mg USD 306 In-stock
100 mg USD 490 In-stock
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Based on 1 publication(s) in Google Scholar

PC Alkyne-PEG4-NHS ester Related Antibodies

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Description

PC Alkyne-PEG4-NHS ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. PC Alkyne-PEG4-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC50 & Target

Cleavable Linker

 

In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

PC Alkyne-PEG4-NHS ester Related Antibodies
Molecular Weight

653.63

Formula

C29H39N3O14
CAS No.
Appearance

Viscous Liquid

Color

Light yellow to yellow

SMILES

O=C(OC(C1=CC(OC)=C(OCCCC(NCCOCCOCCOCCOCC#C)=O)C=C1[N+]([O-])=O)C)ON2C(CCC2=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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PC Alkyne-PEG4-NHS ester Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PC Alkyne-PEG4-NHS ester1802907-98-7ADC LinkerAntibody-drug conjugates linkerInhibitorinhibitorinhibit

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Product Name:
PC Alkyne-PEG4-NHS ester
Cat. No.:
HY-140139
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