DBCO-PEG4-VA-PABC-MMAE
Based on 1 Customer Validation
DBCO-PEG4-VA-PABC-MMAE is a drug-linker conjugate for ADC. DBCO-PEG4-VA-PABC-MMAE consists of a tubulin inhibitor (MMAE) (HY-15162) and a cleavable linker (DBCO-PEG4-VA-PABC). DBCO-PEG4-VA-PABC-MMAE can be used for synthesis of ADC ABBV-400 (HY-171945).
For research use only. We do not sell to patients.
- Purity: 98.94%
- CAS No.: 3049211-57-3
- Formula: C85H122N10O18
- Molecular Weight:1571.93
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Storage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Drug-Linker Conjugates for ADC Isoforms
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Biological Activity
Chemical Information
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CAS No. 3049211-57-3
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Appearance Solid
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Molecular Weight 1571.93
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Formula C85H122N10O18
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Color White to off-white
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SMILES
O=C(N1[C@](CCC1)([H])[C@H](OC)[C@@H](C)C(N[C@H](C)[C@H](C2=CC=CC=C2)O)=O)C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC(C=C3)=CC=C3NC([C@H](C)NC([C@H](C(C)C)NC(CCOCCOCCOCCOCCNC(CCC(N4C5=CC=CC=C5C#CC6=CC=CC=C6C4)=O)=O)=O)=O)=O)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : ≥ 100 mg/mL (63.62 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (264 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.6362 mL | 3.1808 mL | 6.3616 mL | 15.9040 mL |
| 5 mM | 0.1272 mL | 0.6362 mL | 1.2723 mL | 3.1808 mL | |
| 10 mM | 0.0636 mL | 0.3181 mL | 0.6362 mL | 1.5904 mL | |
| 15 mM | 0.0424 mL | 0.2121 mL | 0.4241 mL | 1.0603 mL | |
| 20 mM | 0.0318 mL | 0.1590 mL | 0.3181 mL | 0.7952 mL | |
| 25 mM | 0.0254 mL | 0.1272 mL | 0.2545 mL | 0.6362 mL | |
| 30 mM | 0.0212 mL | 0.1060 mL | 0.2121 mL | 0.5301 mL | |
| 40 mM | 0.0159 mL | 0.0795 mL | 0.1590 mL | 0.3976 mL | |
| 50 mM | 0.0127 mL | 0.0636 mL | 0.1272 mL | 0.3181 mL | |
| 60 mM | 0.0106 mL | 0.0530 mL | 0.1060 mL | 0.2651 mL |
DBCO-PEG4-VA-PABC-MMAE Related Classifications
HY-176765 Related Classifications
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