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Cat. No.: HY-181992

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Mal-PEG4-Val-Cit-PAB-MSA-2

Mal-PEG4-Val-Cit-PAB-MSA-2 is a Drug-Linker Conjugates for ADC. Mal-PEG4-Val-Cit-PAB-MSA-2 consists of the ADC Cytotoxin MSA-2 (HY-136927) and a linker Mal-PEG4-Val-Cit-PAB-OH (HY-140143). Mal-PEG4-Val-Cit-PAB-MSA-2 can be used for synthesis of ADCs.

For research use only. We do not sell to patients.

Formula: C₄₇H₆₂N₆O₁₅S
Molecular Weight:983.09

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Mal-PEG4-Val-Cit-PAB-MSA-2 Chemical Structure

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Biological Activity
- Description
- In Vitro
Chemical Information
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Biological Activity

Description

All Drug-Linker Conjugates for ADC Isoforms :

In Vitro

Mal-PEG4-Val-Cit-PAB-MSA-2 can be used to develop Y101S, an antibody-drug conjugate targeting TGF-β in cancer^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

Molecular Weight 983.09
Formula C₄₇H₆₂N₆O₁₅S
SMILES

O=C(C=CC1=O)N1CCOCCOCCOCCOCCC(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=O)C(NC2=CC=C(COC(CCC(C3=CC4=C(C=C(OC)C(OC)=C4)S3)=O)=O)C=C2)=O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Yi M, et al. Triple targeting of STING, TGF-β, and PD-L1 boosts CXCL16-CXCR6 signaling for potent antitumor response. Nat Commun. 2026;17(1):1441. Published 2026 Feb 9. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
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- In Vitro
Chemical Information
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References

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Mal-PEG4-Val-Cit-PAB-MSA-2

All Drug-Linker Conjugates for ADC Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Mal-PEG4-Val-Cit-PAB-MSA-2 Related Classifications

HY-181992 Related Classifications