Mal-PEG4-Val-Cit-PAB-OH
Based on 1 Customer Validation
Mal-PEG4-Val-Cit-PAB-OH is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
For research use only. We do not sell to patients.
- Purity: 96.92%
- CAS No.: 2055041-39-7
- Formula: C33H50N6O11
- Molecular Weight:706.78
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Storage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Protease Cleavable Linker |
Cleavable Linker |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2055041-39-7
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Appearance Solid
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Molecular Weight 706.78
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Formula C33H50N6O11
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Color White to light yellow
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SMILES
OCC(C=C1)=CC=C1NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCOCCOCCOCCOCCN2C(C=CC2=O)=O)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 125 mg/mL (176.86 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.4149 mL | 7.0743 mL | 14.1487 mL | 35.3717 mL |
| 5 mM | 0.2830 mL | 1.4149 mL | 2.8297 mL | 7.0743 mL | |
| 10 mM | 0.1415 mL | 0.7074 mL | 1.4149 mL | 3.5372 mL | |
| 15 mM | 0.0943 mL | 0.4716 mL | 0.9432 mL | 2.3581 mL | |
| 20 mM | 0.0707 mL | 0.3537 mL | 0.7074 mL | 1.7686 mL | |
| 25 mM | 0.0566 mL | 0.2830 mL | 0.5659 mL | 1.4149 mL | |
| 30 mM | 0.0472 mL | 0.2358 mL | 0.4716 mL | 1.1791 mL | |
| 40 mM | 0.0354 mL | 0.1769 mL | 0.3537 mL | 0.8843 mL | |
| 50 mM | 0.0283 mL | 0.1415 mL | 0.2830 mL | 0.7074 mL | |
| 60 mM | 0.0236 mL | 0.1179 mL | 0.2358 mL | 0.5895 mL | |
| 80 mM | 0.0177 mL | 0.0884 mL | 0.1769 mL | 0.4421 mL | |
| 100 mM | 0.0141 mL | 0.0707 mL | 0.1415 mL | 0.3537 mL |
Mal-PEG4-Val-Cit-PAB-OH Related Classifications
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