1. PROTAC
  2. PROTAC Linker
  3. PROTAC Linker 16

PROTAC Linker 16 

Cat. No.: HY-W004816
Handling Instructions

PROTAC Linker 16 is a polyethylene glycol (PEG)-based PROTAC linker. PROTAC Linker 16 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

For research use only. We do not sell to patients.

PROTAC Linker 16 Chemical Structure

PROTAC Linker 16 Chemical Structure

CAS No. : 37860-51-8

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
100 mg Get quote
100 mg USD 50 In-stock
Estimated Time of Arrival: December 31
250 mg Get quote
500 mg Get quote

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products

View All PROTAC Linker Isoform Specific Products:

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

PROTAC Linker 16 is a polyethylene glycol (PEG)-based PROTAC linker. PROTAC Linker 16 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

IC50 & Target

PEGs

 

Molecular Weight

502.60

Formula

C₂₂H₃₀O₉S₂

CAS No.

37860-51-8

SMILES

O=S(C1=CC=C(C)C=C1)(OCCOCCOCCOCCOS(C2=CC=C(C)C=C2)(=O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Pure form -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Inquiry Online

Your information is safe with us. * Required Fields.

Product name

 

Salutation

Applicant name *

 

Email address *

Phone number *

 

Organization name *

Country or Region *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
PROTAC Linker 16
Cat. No.:
HY-W004816
Quantity: