Cl-C6-PEG4-C3-COOH
Based on 1 Customer Validation
Cl-C6-PEG4-C3-COOH is a PROTAC linker can be used in the synthesis of chloroalkane-containing PROTACs (HaloPROTACs).
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- Pureté : 99.65%
- CAS No.: 2127391-58-4
- Formule: C18H35ClO6
- Masse moléculaire:382.92
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Stockage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Activité biologique
Description
IC50 & Target
[1]|
PEGs |
Chemical Information
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CAS No. 2127391-58-4
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Appearance Liquid (Density: 1.072 g/cm3)
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Masse moléculaire 382.92
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Formule C18H35ClO6
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Color Colorless to light yellow
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SMILES
O=C(O)CCCCCOCCOCCOCCOCCCCCCCl
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvant et solubilité
In Vitro:
DMSO : 100 mg/mL (261.15 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
Pureté et documentation
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Fiche technique (262 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.6115 mL | 13.0576 mL | 26.1151 mL | 65.2878 mL |
| 5 mM | 0.5223 mL | 2.6115 mL | 5.2230 mL | 13.0576 mL | |
| 10 mM | 0.2612 mL | 1.3058 mL | 2.6115 mL | 6.5288 mL | |
| 15 mM | 0.1741 mL | 0.8705 mL | 1.7410 mL | 4.3525 mL | |
| 20 mM | 0.1306 mL | 0.6529 mL | 1.3058 mL | 3.2644 mL | |
| 25 mM | 0.1045 mL | 0.5223 mL | 1.0446 mL | 2.6115 mL | |
| 30 mM | 0.0871 mL | 0.4353 mL | 0.8705 mL | 2.1763 mL | |
| 40 mM | 0.0653 mL | 0.3264 mL | 0.6529 mL | 1.6322 mL | |
| 50 mM | 0.0522 mL | 0.2612 mL | 0.5223 mL | 1.3058 mL | |
| 60 mM | 0.0435 mL | 0.2176 mL | 0.4353 mL | 1.0881 mL | |
| 80 mM | 0.0326 mL | 0.1632 mL | 0.3264 mL | 0.8161 mL | |
| 100 mM | 0.0261 mL | 0.1306 mL | 0.2612 mL | 0.6529 mL |