BCN-PEG4-HyNic
BCN-PEG4-HyNic is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). BCN-PEG4-HyNic is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- No. CAS: 1507370-54-8
- Fòrmula: C28H41N5O6
- Peso molecular:543.66
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
IC50 & Target
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Acid Cleavable Linker |
Cleavable Linker |
In Vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 1507370-54-8
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Peso molecular 543.66
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Fòrmula C28H41N5O6
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SMILES
O=C(NCCOCCOCCOCCNC(OC[C@@H]1[C@@]2(CCC#CCC[C@@]21[H])[H])=O)C3=CN=C(N/N=C(C)\C)C=C3
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)