PTDA-PEG4-azide
Based on 1 Customer Validation
PTAD-PEG4-N3 is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). PTAD-PEG4-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
For research use only. We do not sell to patients.
- Purity: 99.34%
- CAS No.: 2639395-40-5
- Formula: C22H33N7O9
- Molecular Weight:539.54
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Storage:Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cleavable Linker |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2639395-40-5
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Appearance Oil
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Molecular Weight 539.54
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Formula C22H33N7O9
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Color White to off-white
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SMILES
O=C(NNC1=O)N1C2=CC=C(OCCNC(CCOCCOCCOCCOCCN=[N+]=[N-])=O)C(OC)=C2
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Synonyms
PTAD-PEG4-N3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 125 mg/mL (231.68 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.8534 mL | 9.2672 mL | 18.5343 mL | 46.3358 mL |
| 5 mM | 0.3707 mL | 1.8534 mL | 3.7069 mL | 9.2672 mL | |
| 10 mM | 0.1853 mL | 0.9267 mL | 1.8534 mL | 4.6336 mL | |
| 15 mM | 0.1236 mL | 0.6178 mL | 1.2356 mL | 3.0891 mL | |
| 20 mM | 0.0927 mL | 0.4634 mL | 0.9267 mL | 2.3168 mL | |
| 25 mM | 0.0741 mL | 0.3707 mL | 0.7414 mL | 1.8534 mL | |
| 30 mM | 0.0618 mL | 0.3089 mL | 0.6178 mL | 1.5445 mL | |
| 40 mM | 0.0463 mL | 0.2317 mL | 0.4634 mL | 1.1584 mL | |
| 50 mM | 0.0371 mL | 0.1853 mL | 0.3707 mL | 0.9267 mL | |
| 60 mM | 0.0309 mL | 0.1545 mL | 0.3089 mL | 0.7723 mL | |
| 80 mM | 0.0232 mL | 0.1158 mL | 0.2317 mL | 0.5792 mL | |
| 100 mM | 0.0185 mL | 0.0927 mL | 0.1853 mL | 0.4634 mL |
PTDA-PEG4-azide Related Classifications
HY-130940 Related Classifications
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