2639395-40-5
Chemical Structure
PTDA-PEG4-azide
Synonym(s): PTAD-PEG4-N3
- CAS No.: 2639395-40-5
- Formula:C22H33N7O9
- Molecular Weight:539.54
IUPAC Name: 1-azido-N-(2-(4-(3,5-dioxo-1,2,4-triazolidin-4-yl)-2-methoxyphenoxy)ethyl)-3,6,9,12-tetraoxapentadecan-15-amide
InChIKey: FEIQZMMASRDUCL-UHFFFAOYSA-N
SMILES: O=C(NNC1=O)N1C2=CC=C(OCCNC(CCOCCOCCOCCOCCN=[N+]=[N-])=O)C(OC)=C2
Biological Activity: PTAD-PEG4-N3 is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. PTAD-PEG4-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
PTDA-PEG4-azide | 99.34% | PTAD-PEG4-N3 is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). PTAD-PEG4-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords
