1. Antibody-drug Conjugate/ADC Related
  2. Drug-Linker Conjugates for ADC
  3. DBCO-PEG4-Ahx-DM1

DBCO-PEG4-Ahx-DM1 

Cat. No.: HY-136260
Handling Instructions

DBCO-PEG4-Ahx-DM1 is a drug-linker conjugate composed of a potent microtubulin inhibitor DM1 and a linker DBCO-PEG4-Ahx to make antibody drug conjugate (ADC). Mertansine (DM1) is a microtubulin inhibitor and is an antibody-conjugatable maytansinoid that is developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery.

For research use only. We do not sell to patients.

DBCO-PEG4-Ahx-DM1 Chemical Structure

DBCO-PEG4-Ahx-DM1 Chemical Structure

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Description

DBCO-PEG4-Ahx-DM1 is a drug-linker conjugate composed of a potent microtubulin inhibitor DM1 and a linker DBCO-PEG4-Ahx to make antibody drug conjugate (ADC). Mertansine (DM1) is a microtubulin inhibitor and is an antibody-conjugatable maytansinoid that is developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery.

IC50 & Target

Maytansinoids

 

Molecular Weight

1297.92

Formula

C₆₈H₈₉ClN₆O₁₇

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Product Name:
DBCO-PEG4-Ahx-DM1
Cat. No.:
HY-136260
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