m-PEG4-SH
Based on 1 Customer Validation
m-PEG4-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 99.84%
- CAS No.: 52190-55-3
- Formula: C9H20O4S
- Molecular Weight:224.32
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Storage:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All PROTAC Linkers Isoforms
More
Biological Activity
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 52190-55-3
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Appearance Liquid (Density: 1.035 g/cm3)
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Molecular Weight 224.32
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Formula C9H20O4S
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Color Colorless to light yellow
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SMILES
COCCOCCOCCOCCS
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
DMSO : ≥ 100 mg/mL (445.79 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (761 KB)
- English - EN (761 KB)
- Français - FR (761 KB)
- Deutsch - DE (761 KB)
- Norwegian - NO (761 KB)
- Español - ES (761 KB)
- Swedish - SV (761 KB)
- Italian - IT (761 KB)
- Korean - KR (761 KB)
- Portuguese - PT (761 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.4579 mL | 22.2896 mL | 44.5792 mL | 111.4479 mL |
| 5 mM | 0.8916 mL | 4.4579 mL | 8.9158 mL | 22.2896 mL | |
| 10 mM | 0.4458 mL | 2.2290 mL | 4.4579 mL | 11.1448 mL | |
| 15 mM | 0.2972 mL | 1.4860 mL | 2.9719 mL | 7.4299 mL | |
| 20 mM | 0.2229 mL | 1.1145 mL | 2.2290 mL | 5.5724 mL | |
| 25 mM | 0.1783 mL | 0.8916 mL | 1.7832 mL | 4.4579 mL | |
| 30 mM | 0.1486 mL | 0.7430 mL | 1.4860 mL | 3.7149 mL | |
| 40 mM | 0.1114 mL | 0.5572 mL | 1.1145 mL | 2.7862 mL | |
| 50 mM | 0.0892 mL | 0.4458 mL | 0.8916 mL | 2.2290 mL | |
| 60 mM | 0.0743 mL | 0.3715 mL | 0.7430 mL | 1.8575 mL | |
| 80 mM | 0.0557 mL | 0.2786 mL | 0.5572 mL | 1.3931 mL | |
| 100 mM | 0.0446 mL | 0.2229 mL | 0.4458 mL | 1.1145 mL |
m-PEG4-SH Related Classifications
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