1. Antibody-drug Conjugate/ADC Related
  2. ADC Linker
  3. Cyclooctyne-O-amido-PEG4-PFP ester

Cyclooctyne-O-amido-PEG4-PFP ester 

Cat. No.: HY-133576
Handling Instructions

Cyclooctyne-O-amido-PEG4-PFP ester is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

For research use only. We do not sell to patients.

Cyclooctyne-O-amido-PEG4-PFP ester Chemical Structure

Cyclooctyne-O-amido-PEG4-PFP ester Chemical Structure

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Description

Cyclooctyne-O-amido-PEG4-PFP ester is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

Molecular Weight

595.55

Formula

C₂₇H₃₄F₅NO₈

SMILES

O=C(OC1=C(F)C(F)=C(F)C(F)=C1F)CCOCCOCCOCCOCCNC(COC2C#CCCCCC2)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Cyclooctyne-O-amido-PEG4-PFP esterADC LinkerAntibody-drug conjugates linkerInhibitorinhibitorinhibit

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Product name:
Cyclooctyne-O-amido-PEG4-PFP ester
Cat. No.:
HY-133576
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