1. PROTAC
  2. E3 Ligase Ligand-Linker Conjugates
  3. Pomalidomide-PEG4-Ph-NH2

Pomalidomide-PEG4-Ph-NH2 (Synonyms: Cereblon Ligand-Linker Conjugates 9; E3 Ligase Ligand-Linker Conjugates 2)

Cat. No.: HY-41549 Purity: ≥98.0%
Handling Instructions

Pomalidomide-PEG4-Ph-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology.

For research use only. We do not sell to patients.

Pomalidomide-PEG4-Ph-NH2 Chemical Structure

Pomalidomide-PEG4-Ph-NH2 Chemical Structure

CAS No. : 1818885-63-0

Size Price Stock Quantity
100 mg USD 550 In-stock
Estimated Time of Arrival: December 31
500 mg USD 1950 In-stock
Estimated Time of Arrival: December 31
1 g USD 3350 Get quote
2 g USD 4900 Get quote
5 g   Get quote  
10 g   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

Pomalidomide-PEG4-Ph-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology.

IC50 & Target

Cereblon

 

Molecular Weight

540.57

Formula

C27H32N4O8

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 50 mg/mL (92.49 mM)

H2O : < 0.1 mg/mL (insoluble)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8499 mL 9.2495 mL 18.4990 mL
5 mM 0.3700 mL 1.8499 mL 3.6998 mL
10 mM 0.1850 mL 0.9249 mL 1.8499 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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Product Name:
Pomalidomide-PEG4-Ph-NH2
Cat. No.:
HY-41549
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