Thalidomide-O-amido-PEG3-C2-NH2 TFA
Based on 1 Customer Validation
Thalidomide-O-amido-PEG3-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.
For research use only. We do not sell to patients.
- Purity: 99.55%
- CAS No.: 1957236-21-3
- Formula: C25H31F3N4O11
- Molecular Weight:620.53
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All E3 Ligase Ligand-Linker Conjugates Isoforms
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Biological Activity
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Cereblon |
Chemical Information
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CAS No. 1957236-21-3
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Appearance Solid
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Molecular Weight 620.53
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Formula C25H31F3N4O11
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Color White to off-white
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SMILES
O=C(N(C(CCC1=O)C(N1)=O)C2=O)C(C2=CC=C3)=C3OCC(NCCOCCOCCOCCN)=O.FC(F)(F)C(O)=O
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Synonyms
Cereblon Ligand-Linker Conjugates 3 TFA; E3 ligase Ligand-Linker Conjugates 14 TFA
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 50 mg/mL (80.58 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.6115 mL | 8.0576 mL | 16.1153 mL | 40.2881 mL |
| 5 mM | 0.3223 mL | 1.6115 mL | 3.2231 mL | 8.0576 mL | |
| 10 mM | 0.1612 mL | 0.8058 mL | 1.6115 mL | 4.0288 mL | |
| 15 mM | 0.1074 mL | 0.5372 mL | 1.0744 mL | 2.6859 mL | |
| 20 mM | 0.0806 mL | 0.4029 mL | 0.8058 mL | 2.0144 mL | |
| 25 mM | 0.0645 mL | 0.3223 mL | 0.6446 mL | 1.6115 mL | |
| 30 mM | 0.0537 mL | 0.2686 mL | 0.5372 mL | 1.3429 mL | |
| 40 mM | 0.0403 mL | 0.2014 mL | 0.4029 mL | 1.0072 mL | |
| 50 mM | 0.0322 mL | 0.1612 mL | 0.3223 mL | 0.8058 mL | |
| 60 mM | 0.0269 mL | 0.1343 mL | 0.2686 mL | 0.6715 mL | |
| 80 mM | 0.0201 mL | 0.1007 mL | 0.2014 mL | 0.5036 mL |
Thalidomide-O-amido-PEG3-C2-NH2 TFA Related Classifications
HY-103611 Related Classifications
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