2. Antibody-drug Conjugate/ADC Related Metabolic Enzyme/Protease Apoptosis
  3. Drug-Linker Conjugates for ADC Glutathione Peroxidase Ferroptosis
  4. RSL3-NH2-Ala-Val-DBCO-PEG4-Maleimide

RSL3-NH2-Ala-Val-DBCO-PEG4-Maleimide is a drug-linker conjugate for ADC. RSL3-NH2-Ala-Val-DBCO-PEG4-Maleimide consists of a GPX4 inhibitor and ferroptosis inducer (RSL3-NH2) (HY-175615) and a linker (H-Ala-Val-OH) (HY-P4955). RSL3-NH2-Ala-Val-DBCO-PEG4-Maleimide can be used for synthesis of ADCs.

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RSL3-NH2-Ala-Val-DBCO-PEG4-Maleimide

RSL3-NH2-Ala-Val-DBCO-PEG4-Maleimide 화학구조

사이즈 재고
50 mg   견적 받기  
100 mg   견적 받기  
250 mg   견적 받기  

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

RSL3-NH2-Ala-Val-DBCO-PEG4-Maleimide Related Antibodies

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Auristatin Camptothecins Daunorubicins/Doxorubicins Duocarmycins Maytansinoids Pyrrolobenzodiazepines Traditional Cytotoxic Agents Dual payloads

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GPX1 GPX4

  • Biological Activity

  • 순도&문서

  • References

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제품 설명

RSL3-NH2-Ala-Val-DBCO-PEG4-Maleimide is a drug-linker conjugate for ADC. RSL3-NH2-Ala-Val-DBCO-PEG4-Maleimide consists of a GPX4 inhibitor and ferroptosis inducer (RSL3-NH2) (HY-175615) and a linker (H-Ala-Val-OH) (HY-P4955). RSL3-NH2-Ala-Val-DBCO-PEG4-Maleimide can be used for synthesis of ADCs[1].

IC50 & Target

GPX4

 

분자량

1353.91

화학식

C69H81ClN12O15
SMILES

O=C(N[C@H](C(N[C@H](C(NC1=CC=C([C@H]2C(NC3=CC=CC=C34)=C4C[C@@H](N2C(CCl)=O)C(OC)=O)C=C1)=O)C)=O)C(C)C)CCCN5N=NC6=C5C7=CC=CC=C7CN(C8=CC=CC=C86)C(CCNC(CCOCCOCCOCCOCCNC(CCN9C(C=CC9=O)=O)=O)=O)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
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RSL3-NH2-Ala-Val-DBCO-PEG4-Maleimide Related Classifications

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  • 농도 희석 계산기

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

RSL3-NH2-Ala-Val-DBCO-PEG4-MaleimideDrug-Linker Conjugates for ADCGlutathione PeroxidaseFerroptosisDrug-linker conjugate for ADCGPX4Inhibitorinhibitorinhibit

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상품명:
RSL3-NH2-Ala-Val-DBCO-PEG4-Maleimide
Cat. No.:
HY-175614
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