Propargyl-PEG4-GGFG-DXd
Based on 1 Customer Validation
Propargyl-PEG4-GGFG-DXd is a drug-linker conjugate for ADC. Propargyl-PEG4-GGFG-DXd contains a ADC linker and a DNA topoisomerase I inhibitor DXd (HY-13631D).
For research use only. We do not sell to patients.
- Purity: 98.69%
- CAS No.: 2762518-94-3
- Formula: C54H63FN8O15
- Molecular Weight:1083.12
-
Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
All Drug-Linker Conjugates for ADC Isoforms
More
Biological Activity
Chemical Information
-
CAS No. 2762518-94-3
-
Appearance Solid
-
Molecular Weight 1083.12
-
Formula C54H63FN8O15
-
Color Off-white to light yellow
-
SMILES
C#CCOCCOCCOCCOCCC(NCC(NCC(N[C@@H](CC1=CC=CC=C1)C(NCC(NCOCC(N[C@@H]2C3=C4C(C(N5C4)=CC([C@](O)(C(OC6)=O)CC)=C6C5=O)=NC7=CC(F)=C(C)C(CC2)=C73)=O)=O)=O)=O)=O)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 100 mg/mL (92.33 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (266 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.9233 mL | 4.6163 mL | 9.2326 mL | 23.0815 mL |
| 5 mM | 0.1847 mL | 0.9233 mL | 1.8465 mL | 4.6163 mL | |
| 10 mM | 0.0923 mL | 0.4616 mL | 0.9233 mL | 2.3081 mL | |
| 15 mM | 0.0616 mL | 0.3078 mL | 0.6155 mL | 1.5388 mL | |
| 20 mM | 0.0462 mL | 0.2308 mL | 0.4616 mL | 1.1541 mL | |
| 25 mM | 0.0369 mL | 0.1847 mL | 0.3693 mL | 0.9233 mL | |
| 30 mM | 0.0308 mL | 0.1539 mL | 0.3078 mL | 0.7694 mL | |
| 40 mM | 0.0231 mL | 0.1154 mL | 0.2308 mL | 0.5770 mL | |
| 50 mM | 0.0185 mL | 0.0923 mL | 0.1847 mL | 0.4616 mL | |
| 60 mM | 0.0154 mL | 0.0769 mL | 0.1539 mL | 0.3847 mL | |
| 80 mM | 0.0115 mL | 0.0577 mL | 0.1154 mL | 0.2885 mL |