Me-PEG4-Me
Based on 1 Customer Validation
Me-PEG4-Me is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 99.93%
- CAS No.: 143-24-8
- Formula: C10H22O5
- Molecular Weight:222.28
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All PROTAC Linkers Isoforms
More
Biological Activity
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 143-24-8
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Appearance Liquid (Density: 1.009 g/cm3 )
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Molecular Weight 222.28
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Formula C10H22O5
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Color Colorless to light yellow
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SMILES
COCCOCCOCCOCCOC
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Synonyms
Tetraglyme
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H2O : ≥ 100 mg/mL (449.88 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (418 KB)
- English - EN (418 KB)
- Français - FR (418 KB)
- Deutsch - DE (418 KB)
- Norwegian - NO (418 KB)
- Español - ES (418 KB)
- Swedish - SV (418 KB)
- Italian - IT (418 KB)
- Korean - KR (418 KB)
- Portuguese - PT (418 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 4.4988 mL | 22.4942 mL | 44.9883 mL | 112.4708 mL |
| 5 mM | 0.8998 mL | 4.4988 mL | 8.9977 mL | 22.4942 mL | |
| 10 mM | 0.4499 mL | 2.2494 mL | 4.4988 mL | 11.2471 mL | |
| 15 mM | 0.2999 mL | 1.4996 mL | 2.9992 mL | 7.4981 mL | |
| 20 mM | 0.2249 mL | 1.1247 mL | 2.2494 mL | 5.6235 mL | |
| 25 mM | 0.1800 mL | 0.8998 mL | 1.7995 mL | 4.4988 mL | |
| 30 mM | 0.1500 mL | 0.7498 mL | 1.4996 mL | 3.7490 mL | |
| 40 mM | 0.1125 mL | 0.5624 mL | 1.1247 mL | 2.8118 mL | |
| 50 mM | 0.0900 mL | 0.4499 mL | 0.8998 mL | 2.2494 mL | |
| 60 mM | 0.0750 mL | 0.3749 mL | 0.7498 mL | 1.8745 mL | |
| 80 mM | 0.0562 mL | 0.2812 mL | 0.5624 mL | 1.4059 mL | |
| 100 mM | 0.0450 mL | 0.2249 mL | 0.4499 mL | 1.1247 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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