1. PROTAC
  2. PROTAC Linker
  3. Azido-PEG3-Sulfone-PEG4-acid

Azido-PEG3-Sulfone-PEG4-acid 

Cat. No.: HY-140602
Handling Instructions

Azido-PEG3-Sulfone-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

Azido-PEG3-Sulfone-PEG4-acid Chemical Structure

Azido-PEG3-Sulfone-PEG4-acid Chemical Structure

CAS No. : 2055024-42-3

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Description

Azido-PEG3-Sulfone-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Molecular Weight

515.58

Formula

C₁₉H₃₇N₃O₁₁S

CAS No.

2055024-42-3

SMILES

O=C(O)CCOCCOCCOCCOCCS(CCOCCOCCOCCN=[N+]=[N-])(=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Azido-PEG3-Sulfone-PEG4-acidPROTAC LinkerInhibitorinhibitorinhibit

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Azido-PEG3-Sulfone-PEG4-acid
Cat. No.:
HY-140602
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