Carboxyrhodamine 110-PEG4-DBCO
Carboxyrhodamine 110-PEG4-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Carboxyrhodamine 110-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
For research use only. We do not sell to patients.
- Formula: C50H49N5O10
- Molecular Weight:879.97
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All PROTAC Linkers Isoforms
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Biological Activity
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 879.97
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Formula C50H49N5O10
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SMILES
[O-]C(C1=C(C2=C3C=CC(C=C3OC4=C2C=CC(N)=C4)=[NH2+])C=C(C(NCCOCCOCCOCCOCCC(NCCC(N5C6=C(C#CC7=C(C5)C=CC=C7)C=CC=C6)=O)=O)=O)C=C1)=O.[O-]C(C8=C(C(C9=C(O%10)C=C(N)C=C9)=C(C=C%11)C%10=CC%11=[NH2+])C=CC(C(NCCOCCOCCOCCOCCC(NCCC(N%12C%13=C(C#CC%14=C(C%12)C=CC=C%14)C=CC=C%13)=O)=O)=O)=C8)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Carboxyrhodamine 110-PEG4-DBCO Related Classifications
HY-140297 Related Classifications
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