3,4-Dibromo-Mal-PEG4-Acid
Based on 1 Customer Validation
3,4-Dibromo-Mal-PEG4-acid is a site specific ADC linker with a dibromomaleimide group and an acid group. The dibromomaleimide group allows for two points of substitution due to the two bromine atoms. The carboxylic acid can react with primary amines in the presence of EDC and HATU to form a stable amide bond. The hydrophilic PEG linker increases the water solubility of compounds in aqueous media.
For research use only. We do not sell to patients.
- Purity: 95.20%
- CAS No.: 2434639-17-3
- Formula: C15H21Br2NO8
- Molecular Weight:503.14
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 2434639-17-3
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Appearance Solid
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Molecular Weight 503.14
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Formula C15H21Br2NO8
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Color Off-white to light yellow
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SMILES
O=C(CCOCCOCCOCCOCCN1C(C(Br)=C(C1=O)Br)=O)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (198.75 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (239 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.9875 mL | 9.9376 mL | 19.8752 mL | 49.6880 mL |
| 5 mM | 0.3975 mL | 1.9875 mL | 3.9750 mL | 9.9376 mL | |
| 10 mM | 0.1988 mL | 0.9938 mL | 1.9875 mL | 4.9688 mL | |
| 15 mM | 0.1325 mL | 0.6625 mL | 1.3250 mL | 3.3125 mL | |
| 20 mM | 0.0994 mL | 0.4969 mL | 0.9938 mL | 2.4844 mL | |
| 25 mM | 0.0795 mL | 0.3975 mL | 0.7950 mL | 1.9875 mL | |
| 30 mM | 0.0663 mL | 0.3313 mL | 0.6625 mL | 1.6563 mL | |
| 40 mM | 0.0497 mL | 0.2484 mL | 0.4969 mL | 1.2422 mL | |
| 50 mM | 0.0398 mL | 0.1988 mL | 0.3975 mL | 0.9938 mL | |
| 60 mM | 0.0331 mL | 0.1656 mL | 0.3313 mL | 0.8281 mL | |
| 80 mM | 0.0248 mL | 0.1242 mL | 0.2484 mL | 0.6211 mL | |
| 100 mM | 0.0199 mL | 0.0994 mL | 0.1988 mL | 0.4969 mL |
3,4-Dibromo-Mal-PEG4-Acid Related Classifications
HY-W591402 Related Classifications
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