N-(Mal-PEG4)-N-(PEG4-Val-Cit-PAB-MMAE)-N-(PEG4-Val-Cit-PAB-Exatecan)
N-(Mal-PEG4)-N-(PEG4-Val-Cit-PAB-MMAE)-N-(PEG4-Val-Cit-PAB-Exatecan) is a drug-linker conjugate for ADC (Drug-Linker Conjugate for ADC), consisting of a tubulin polymerization inhibitor MMAE (HY-15162) and a DNA topoisomerase I inhibitor Exatecan (HY-13631), and an ADC linker composition. N-(Mal-PEG4)-N-(PEG4-Val-Cit-PAB-MMAE)-N-(PEG4-Val-Cit-PAB-Exatecan) can be used for synthesis of ADCs and for cancer research.
For research use only. We do not sell to patients.
- Formula: C138H203FN20O38
- Molecular Weight:2769.20
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
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Help & FAQs
Biological Activity
Description
In Vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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Molecular Weight 2769.20
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Formula C138H203FN20O38
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SMILES
O=C(N(CCOCCOCCOCCOCCC(N[C@H](C(N[C@H](C(NC1=CC=C(COC(N[C@H]2CCC3=C4C2=C5C(C(N6C5)=CC([C@](O)7CC)=C(C6=O)COC7=O)=NC4=CC(F)=C3C)=O)C=C1)=O)CCCNC(N)=O)=O)C(C)C)=O)CCOCCOCCOCCOCCC(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=O)C(NC8=CC=C(COC(N(C)[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N([C@@H]([C@@H](C)CC)[C@H](OC)CC(N9[C@H]([C@H](OC)[C@@H](C)C(N[C@H](C)[C@@H](O)C%10=CC=CC=C%10)=O)CCC9)=O)C)=O)=O)=O)C=C8)=O)=O)=O)CCOCCOCCOCCOCCN%11C(C=CC%11=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
N-(Mal-PEG4)-N-(PEG4-Val-Cit-PAB-MMAE)-N-(PEG4-Val-Cit-PAB-Exatecan) Related Classifications
HY-177680 Related Classifications
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