DBCO-NHCO-PEG4-amine TFA
Based on 1 Customer Validation
DBCO-NHCO-PEG4-amine TFA is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-NHCO-PEG4-amine TFA is a cleavable ADC linker used to conjugate MMAE (HY-15162) and antibody (e.g., DBCO-VCpAB MMAE and DBCO-TRX MMAE with EC50s of 280 nM and 22 nM in SKBR3 cells, respectively).
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 96.74%
- 分子式: C31H38F3N3O8
- 分子量:637.64
-
保管条件:Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
-
溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
PROTAC Linkers アイソフォーム固有の製品をすべて表示
More
生物活性
|
PEGs |
Cleavable Linker |
化学情報
-
性状 Oil
-
分子量 637.64
-
分子式 C31H38F3N3O8
-
Color Light yellow to brown
-
SMILES
O=C(N1CC2=C(C#CC3=C1C=CC=C3)C=CC=C2)CCNC(CCOCCOCCOCCOCCN)=O.O=C(O)C(F)(F)F
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
H2O : 50 mg/mL (78.41 mM; ultrasonic and warming and heat to 60°C)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
-
データシート (268 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 1.5683 mL | 7.8414 mL | 15.6828 mL | 39.2071 mL |
| 5 mM | 0.3137 mL | 1.5683 mL | 3.1366 mL | 7.8414 mL | |
| 10 mM | 0.1568 mL | 0.7841 mL | 1.5683 mL | 3.9207 mL | |
| 15 mM | 0.1046 mL | 0.5228 mL | 1.0455 mL | 2.6138 mL | |
| 20 mM | 0.0784 mL | 0.3921 mL | 0.7841 mL | 1.9604 mL | |
| 25 mM | 0.0627 mL | 0.3137 mL | 0.6273 mL | 1.5683 mL | |
| 30 mM | 0.0523 mL | 0.2614 mL | 0.5228 mL | 1.3069 mL | |
| 40 mM | 0.0392 mL | 0.1960 mL | 0.3921 mL | 0.9802 mL | |
| 50 mM | 0.0314 mL | 0.1568 mL | 0.3137 mL | 0.7841 mL | |
| 60 mM | 0.0261 mL | 0.1307 mL | 0.2614 mL | 0.6535 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
DBCO-NHCO-PEG4-amine TFA 関連分類
HY-124386A 関連分類
Powered by Bioz