N-(azide-PEG3)-N'-(m-PEG4)-Benzothiazole Cy5
N-(azide-PEG3)-N'-(m-PEG4)-Benzothiazole Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. N-(azide-PEG3)-N'-(m-PEG4)-Benzothiazole Cy5 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
For research use only. We do not sell to patients.
- CAS No.: 2107273-88-9
- Formula: C39H54ClN5O7S
- Molecular Weight:772.39
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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HY-141053
N-(m-PEG4)-N'-(m-PEG4)-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy5 -
HY-141067
N-methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy5 -
HY-141049
N-methyl-N'-(propargyl-PEG4)-Cy5 -
HY-141063
N-(m-PEG4)-N'-(azide-PEG3)-Cy5 -
HY-141041
N-(Azide-PEG3)-N'-(PEG4-acid)-Cy5 -
HY-141050
N-PEG3-N'-(propargyl-PEG4)-Cy5 -
HY-141052
N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy5 -
HY-141065
N-(azide-PEG3)-N'-(Amine-C3-Amide-PEG4)-Cy5 -
HY-141054
N,N'-bis-(propargyl-PEG4)-Cy5 -
HY-141068
N-(m-PEG4)-N'-(m-PEG4)-O-(m-PEG4)-O'-(azide-PEG4)-Cy5 -
HY-141061
N-PEG3-N'-(azide-PEG3)-Cy5 -
HY-141032
N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy3
All PROTAC Linkers Isoforms
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Biological Activity
Description
IC50 & Target
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PEGs |
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2107273-88-9
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Molecular Weight 772.39
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Formula C39H54ClN5O7S
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SMILES
COCCOCCOCCOCC[N+]1=C(/C=C/C=C/C=C2N(CCOCCOCCOCCN=[N+]=[N-])C3=C(C=CC=C3)C/2(C)C)SC4=CC=CC=C14.[Cl-]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
N-(azide-PEG3)-N'-(m-PEG4)-Benzothiazole Cy5 Related Classifications
HY-141064 Related Classifications
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