N-(Azide-PEG3)-N'-(PEG4-acid)-Cy5
N-(Azide-PEG3)-N'-(PEG4-acid)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. N-(Azide-PEG3)-N'-(PEG4-acid)-Cy5 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- No. CAS: 2107273-42-5
- Fòrmula: C44H62ClN5O9
- Peso molecular:840.44
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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HY-141053
N-(m-PEG4)-N'-(m-PEG4)-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy5 -
HY-141067
N-methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy5 -
HY-141049
N-methyl-N'-(propargyl-PEG4)-Cy5 -
HY-141063
N-(m-PEG4)-N'-(azide-PEG3)-Cy5 -
HY-141050
N-PEG3-N'-(propargyl-PEG4)-Cy5 -
HY-141052
N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy5 -
HY-141065
N-(azide-PEG3)-N'-(Amine-C3-Amide-PEG4)-Cy5 -
HY-141064
N-(azide-PEG3)-N'-(m-PEG4)-Benzothiazole Cy5 -
HY-141054
N,N'-bis-(propargyl-PEG4)-Cy5 -
HY-141068
N-(m-PEG4)-N'-(m-PEG4)-O-(m-PEG4)-O'-(azide-PEG4)-Cy5 -
HY-141061
N-PEG3-N'-(azide-PEG3)-Cy5 -
HY-141032
N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy3
Ver todos los productos específicos de isoformas PROTAC Linkers
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Actividad biológica
Descripciòn
IC50 & Target
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PEGs |
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 2107273-42-5
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Peso molecular 840.44
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Fòrmula C44H62ClN5O9
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SMILES
CC1(C)C2=C(C=CC=C2)[N+](CCOCCOCCOCCOCCC(O)=O)=C1/C=C/C=C/C=C3C(C)(C)C(C=CC=C4)=C4N\3CCOCCOCCOCCN=[N+]=[N-].[Cl-]
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
N-(Azide-PEG3)-N'-(PEG4-acid)-Cy5 Related Classifications
HY-141041 Related Classifications
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