2107273-42-5
Chemical Structure
N-(Azide-PEG3)-N'-(PEG4-acid)-Cy5
- CAS No.: 2107273-42-5
- Formula:C44H62ClN5O9
- Molecular Weight:840.44
IUPAC Name: 2-((1E,3E)-5-((E)-1-(2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethyl)-3,3-dimethylindolin-2-ylidene)penta-1,3-dien-1-yl)-1-(14-carboxy-3,6,9,12-tetraoxatetradecyl)-3,3-dimethyl-3H-indol-1-ium chloride
InChIKey: UKACGQMFZSBZHG-UHFFFAOYSA-N
SMILES: CC1(C)C2=C(C=CC=C2)[N+](CCOCCOCCOCCOCCC(O)=O)=C1/C=C/C=C/C=C3C(C)(C)C(C=CC=C4)=C4N\3CCOCCOCCOCCN=[N+]=[N-].[Cl-]
Biological Activity: N-(Azide-PEG3)-N'-(PEG4-acid)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-(Azide-PEG3)-N'-(PEG4-acid)-Cy5 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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N-(Azide-PEG3)-N'-(PEG4-acid)-Cy5 | N-(Azide-PEG3)-N'-(PEG4-acid)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. N-(Azide-PEG3)-N'-(PEG4-acid)-Cy5 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | |||||||||||||||||||||
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