TCO-PEG4-NHS ester
Based on 1 Customer Validation
TCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. TCO-PEG4-NHS ester is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit: 99.16%
- CAS. Nr.: 1621096-79-4
- Formel: C24H38N2O10
- Molecular Weight:514.57
-
Speicherung:Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biologische Aktivität
-
Chemical Information
-
Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
-
Help & FAQs
Alle PROTAC Linkers Isoform-spezifische Produkte anzeigen
More
Biologische Aktivität
|
PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS. Nr. 1621096-79-4
-
Appearance Liquid (Density: 1.23±0.1 g/cm3)
-
Molecular Weight 514.57
-
Formel C24H38N2O10
-
Color Colorless to light yellow
-
SMILES
O=C(OC1CC/C=C/CCC1)NCCOCCOCCOCCOCCC(ON2C(CCC2=O)=O)=O
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
DMSO : ≥ 100 mg/mL (194.34 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
-
Data Sheet (267 KB)
-
SDS (419 KB)
- English - EN (419 KB)
- Français - FR (419 KB)
- Deutsch - DE (419 KB)
- Norwegian - NO (419 KB)
- Español - ES (419 KB)
- Swedish - SV (419 KB)
- Italian - IT (419 KB)
- Korean - KR (419 KB)
- Portuguese - PT (419 KB)
-
Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.9434 mL | 9.7169 mL | 19.4337 mL | 48.5843 mL |
| 5 mM | 0.3887 mL | 1.9434 mL | 3.8867 mL | 9.7169 mL | |
| 10 mM | 0.1943 mL | 0.9717 mL | 1.9434 mL | 4.8584 mL | |
| 15 mM | 0.1296 mL | 0.6478 mL | 1.2956 mL | 3.2390 mL | |
| 20 mM | 0.0972 mL | 0.4858 mL | 0.9717 mL | 2.4292 mL | |
| 25 mM | 0.0777 mL | 0.3887 mL | 0.7773 mL | 1.9434 mL | |
| 30 mM | 0.0648 mL | 0.3239 mL | 0.6478 mL | 1.6195 mL | |
| 40 mM | 0.0486 mL | 0.2429 mL | 0.4858 mL | 1.2146 mL | |
| 50 mM | 0.0389 mL | 0.1943 mL | 0.3887 mL | 0.9717 mL | |
| 60 mM | 0.0324 mL | 0.1619 mL | 0.3239 mL | 0.8097 mL | |
| 80 mM | 0.0243 mL | 0.1215 mL | 0.2429 mL | 0.6073 mL | |
| 100 mM | 0.0194 mL | 0.0972 mL | 0.1943 mL | 0.4858 mL |
TCO-PEG4-NHS ester Related Classifications
HY-141167A Related Classifications
Powered by Bioz