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Cat. No.: HY-139726

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Mal-PEG4-Val-Cit-PAB-MMAE

Customer Review

Based on 1 Customer Validation

Mal-PEG4-Val-Cit-PAB-MMAE is part of a drug-linker conjugate for ADC. Mal-PEG4-Val-Cit-PAB-MMAE contains a degradable ADC linker Mal-PEG4-Val-Cit-PAB (HY-126672) and a potent tubulin inhibitor MMAE (HY-15162).

For research use only. We do not sell to patients.

Purity: 98.00%
Formula: C₇₃H₁₁₅N₁₁O₁₉
Molecular Weight:1450.76

Storage:

-20°C, sealed storage, away from moisture

* The compound is unstable in solutions, freshly prepared is recommended.

Mal-PEG4-Val-Cit-PAB-MMAE Chemical Structure

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Top Publications Citing

Use of MCE Products

One-stop CDMO Service

One-Stop Platform：From Independent R&D to Pilot-Scale Production

Biological Activity

Description

All Drug-Linker Conjugates for ADC Isoforms :

Chemical Information

Appearance Solid
Molecular Weight 1450.76
Formula C₇₃H₁₁₅N₁₁O₁₉
Color White to off-white
SMILES

CN([C@@H]([C@@H](C)CC)[C@H](OC)CC(N1[C@H]([C@H](OC)[C@@H](C)C(N[C@H](C)[C@@H](O)C2=CC=CC=C2)=O)CCC1)=O)C([C@H](C(C)C)NC([C@H](C(C)C)N(C(OCC3=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCOCCOCCOCCOCCN4C(C=CC4=O)=O)=O)=O)=O)C=C3)=O)C)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

* The compound is unstable in solutions, freshly prepared is recommended.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody–drug conjugates[J]. Nature reviews Drug discovery, 2017, 16(5): 315-337. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Biological Activity
- Description
Chemical Information
Purity & Documentation
References

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Mal-PEG4-Val-Cit-PAB-MMAE

All Drug-Linker Conjugates for ADC Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Mal-PEG4-Val-Cit-PAB-MMAE Related Classifications

HY-139726 Related Classifications